1,3-二烯烃的羰基化反应研究进展  

Recent Advances on Carbonylation of 1,3-Dienes

作　　者：王鹏[1] 杨妲 刘欢 Wang Peng;Yang Da;Liu Huan(State Key Laboratory of Organometallic Chemistry,Shanghai Institute of Organic Chemistry,Chinese Academy of Sciences,Shanghai 200032;Department of Chemistry,College of Science,China University of Petroleum(East China),Qingdao,Shandong 266580)

机构地区：[1]中国科学院上海有机化学研究所金属有机化学国家重点实验室,上海200032 [2]中国石油大学(华东)理学院化学系,山东青岛266580

出　　处：《有机化学》2021年第9期3379-3389,共11页Chinese Journal of Organic Chemistry

基　　金：国家自然科学基金青年(No.21901250);中国博士后科学基金面上(No.2019M651625)资助项目.

摘　　要：1,3-丁二烯是石脑油裂解过程C4馏分中最主要的组分,通过羰基化反应合成的下游产品己二醛、己二酸、己二酸二甲酯在尼龙、增塑剂、医药中间体等的生产上有重要应用.但是如何高效高化学/区域选择性合成这类高附加值产品一直是有机化学研究以及工业化生产的难题.综述了近年来1,3-二烯类化合物(特别是1,3-丁二烯)发生羰基化反应(氢甲酰化反应、氢酯化反应、氢羧基化反应)构建高附加值化学品的研究进展,并对该方法存在的难点以及未来发展方向进行了阐述和展望.1,3-Butadiene is the main component of C4 fraction in naphtha cracking process.The products of 1,3-butadiene carbonylation(hexanedial,adipic acid and dimethyl adipate)can be used in the production of nylon,plasticizer and pharmaceutical intermediates.How to efficiently and high chemo-/regio-selectivity synthesize these high value-added products has always been a difficult problem in organic chemistry research and industrial production.In this paper,the research progress of carbonylation(hydroformylation,hydroesterification,hydrocarboxylation)of 1,3-dienes(especially 1,3-butadiene)to construct high value-added chemicals in recent years is reviewed,then the difficulties and future development of this method are prospected.

关 键 词：1 3-丁二烯 氢甲酰化反应 氢酯化反应 合成气 均相催化 

分 类 号：O621.25[理学—有机化学]