快速现场细胞学评价联合四维导航引导CT肺穿刺活检术在肺部疾病诊断中的应用探讨  

Exploration on the application of ROSE combined with needle biopsy of lung with guided CT by 4D navigation in the diagnosis of pulmonary diseases

作　　者：张乐天[1] 王钧[1] 张莹[2] 李星虹 王晓林 ZHANG Le-tian;WANG Jun;ZHANG Ying(Department of Respiratory Medicine,Hebei Chest Hospital,Shijiazhuang 050041,China;不详)

机构地区：[1]河北省胸科医院呼吸内科,河北石家庄050041 [2]河北省胸科医院放射科,河北石家庄050041 [3]河北医科大学第二医院康复一科,河北石家庄050073

出　　处：《中国医学装备》2021年第10期75-78,共4页China Medical Equipment

基　　金：河北省2019年度医学科学研究课题计划(20190992)“ROSE联合四维导航引导CT穿刺活检术在肺部病变诊断的意义”。

摘　　要：目的:探讨快速现场细胞学评价(ROSE)联合四维导航引导X射线计算机断层摄影(CT)肺穿刺活检术在肺部疾病诊断中的应用价值。方法:选取医院收治的74例肺部疾病患者,依据穿刺活检术方法的不同将其分为观察组(35例)和对照组(39例)。对比两组平均穿刺针数、穿刺标本合格率及并发症(咯血、气胸)发生情况,并将穿刺活检术后组织病理结果与临床确诊结果进行对比,判定诊断符合率。结果:两组平均穿刺针数比较差异无统计学意义,观察组穿刺标本合格率(100.00%)高于对照组(87.18%),差异有统计学意义(x^(2)=4.812,P<0.05);两组总并发症发生率比较差异无统计学意义;对照组疾病诊断符合率为82.35%,观察组疾病诊断符合率为97.14%,观察组疾病诊断符合率高于对照组,差异有统计学意义(x^(2)=4.138,P<0.05)。结论:在肺部疾病的诊断中应用ROSE联合四维导航引导CT肺穿刺活检术,可提高穿刺标本合格率及疾病诊断符合率,且未增加穿刺针数及并发症的发生,可为临床肺部恶性病变的早期筛查及治疗提供支持与帮助。Objective:To investigate the application value of rapid on-site evaluation(ROSE)combined with needle biopsy of lung with the guidance of computed tomography(CT)that was guided by four-dimensional(4D)navigation in the diagnosis of pulmonary diseases.Methods:79 patients with pulmonary disease who admitted to hospital were selected.They were divided into observation group(35 cases)and control group(39 cases)according to different needle biopsy methods.The average number of the times of puncture,qualified rate of the punctured specimens and the occurrences of complications(hemoptysis and pneumothorax)between the two groups were compared.And then the histopathological results after needle biopsy were compared with the results of clinical confirmation so as to determine the diagnostic accordance rate.Results:There was no significant difference in the average number of the times of puncture between the two groups,but the qualified rate of punctured specimens of observation group(100.00%)was significantly higher than that of control group(87.18%),and the difference of that between the two groups was statistically significant(x^(2)=4.812,P<0.05).There was no significant difference in the incidence of total complications between the two groups.The diagnostic accordance rate of control group was 82.35%,but that of observation group was 97.14%,and the diagnostic accordance rate of observation group was significantly higher than that of control group(x^(2)=4.138,P<0.05).Conclusion:In the diagnosis of pulmonary diseases,the application of ROSE combined with needle biopsy of lung with guidance of computed tomography(CT)that is guided by four-dimensional(4D)navigation can improve the qualified rate of punctured specimens and the diagnostic accordance rate of disease,and it does not increase the number of the times of puncture and the occurrence of complications,which can provide support and help for the early screening and treatment of clinical malignant lesions in lung.

关 键 词：快速现场细胞学评价(ROSE) 四维导航 X射线计算机断层摄影(CT) 肺穿刺活检术 肺部疾病 诊断价值 

分 类 号：R816.4[医药卫生—放射医学]