肺静脉前庭放射状线性消融改良术式治疗持续性房颤——临床Pilot研究  

Pulmonary vein antrum radial linear ablation for persistent atrial fibrillation-Clinical Pilot study

作　　者：彭飞 连晓雨 张和细 胡建强[2] 赵学 龚辉 PENG Fei;LIAN Xiaoyu;ZHANG Hexi;HU Jianqiang;ZHAO Xue;GONG Hui(Department of Cardiology,Jinshan Hospital,Fudan University,Shanghai,200540,China;Department of Cardiology,the First Affiliated Hospital of Second Military Medical University;Department of Cardiology,the Third Affiliated Hospital of Second Military Medical University)

机构地区：[1]复旦大学附属金山医院心血管内科,上海200540 [2]第二军医大学第一附属医院心内科 [3]第二军医大学第三附属医院心内科

出　　处：《临床心血管病杂志》2021年第9期801-804,共4页Journal of Clinical Cardiology

基　　金：复旦大学附属金山医院青年启动基金(No:JYQN-LC-202007)。

摘　　要：目的:在肺静脉前庭放射状线性(PAR)消融术治疗阵发性心房颤动(房颤)的基础上,探讨PAR消融改良术式联合低电压消融治疗持续性房颤的临床疗效。方法:持续性房颤患者35例,男22例,女13例,年龄(63.1±8.6)岁,房颤持续时间(7.3±2.9)个月。用CARTO3三维左房建模,完成PAR消融术,术后服抗心律失常药物(AAD)3个月,术后6、12和24个月以Holter随访。结果:随访(26±7)个月,失访1例(2.9%)。单次消融未服AAD时无房颤率在6个月为25/35例(71%),12个月为22/35例(63%),24个月为19/35例(54%);空白期后,其中1例阵发房颤者继服AAD无房颤发作。本组总体无房颤率6个月为26/35例(74%),12个月为23/35例(66%),24个月为20/35例(57%)。结论:PAR消融改良术式结合低电压区消融对持续房颤临床疗效满意,安全性高,提高生活质量,值得进一步临床研究。Objective:To explore pulmonary vein antrum radial linear(PAR)ablation in the treatment of per-sistent atrial fibrillation.Methods:We used CARTO3to model the left atrium to complete the PAR ablation.Patients took antiarrhythmic drugs(AAD)for 3months after surgery,and followed up with Holter for 72hours at 6,12,and 24months after surgery.Results:In follow-up 26±7months,there was 1case lost(2.9%).The rate of non atrial fibrillation without AAD was 25/35(71%)at 6months,22/35(63%)at 12months,and 19/35(54%)at 24months.The overall rate of atrial fibrillation-free was 26/35cases(74%)at 6months,23/35cases(66%)at 12months,and 20/35cases(57%)at 24months.Conclusion:Modified PAR ablation is safe and effective in persistent atrial fibrillation.

关 键 词：心房颤动 肺静脉前庭放射状线性消融 肺静脉隔离 

分 类 号：R541.7[医药卫生—心血管疾病]