环境与儿童健康研究的设计:现状与发展  

Designs of studies on environment and children’s health: Current status and development

作　　者：周志俊[1] 陶芳标[2] ZHOU Zhijun;TAO Fangbiao(School of Public Health/Key Laboratory of Public Health Safety of Ministry of Education,Fudan University,Shanghai 200032,China;Department of Maternal,Child and Adolescent Health,School of Public Health/MOE Key Laboratory of Population Health Across Life Cycle/Anhui Provincial Key Laboratory of Population Health and Aristogenics/NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract,Anhui Medical University,Hefei,Anhui 230032,China)

机构地区：[1]复旦大学公共卫生学院/公共卫生安全教育部重点实验室,上海200032 [2]安徽医科大学公共卫生学院儿少卫生与妇幼保健学系/出生人口健康教育部重点实验室/人口健康与优生安徽省重点实验室/国家卫生健康委配子及生殖道异常研究重点实验室,安徽合肥230032

出　　处：《环境与职业医学》2021年第9期924-929,共6页Journal of Environmental and Occupational Medicine

基　　金：国家重点研发计划(2018YFC1004200)。

摘　　要：儿童健康是全民健康和素质的基础,对儿童的终身发展至关重要。生命早期经历不良环境因素,往往会对儿童健康产生深远影响。本文从不同研究设计角度出发,介绍了环境与儿童健康相关研究的现状,探讨了不同研究设计存在的不足,包括:因果方向的不确定性,研究的论证力度不足,大样本、前瞻性、多中心、代表性出生队列研究的缺乏。因此,需要加强出生队列建设,为环境与儿童健康相关公共卫生政策的制定提供高质量证据。Children’s health is the foundation of the health and well-being of the entire population, and it is vital to the life-long development of children. Exposure to adverse environmental factors in early life has a lifelong impact on children’s health. From the perspective of different research designs, this review introduced the current status of research related to environment and children’s health and pointed out the short comings of the applied designs, including uncertain causality, insufficient strength of evidence, and lack of large-sample, prospective, multi-center, and representative birth cohort studies. Therefore, it is necessary to strengthen the establishment of birth cohorts to provide high-quality evidence for the formulation of public health policies related to environment and children’s health.

关 键 词：出生队列 生命早期 环境 儿童健康 

分 类 号：R12[医药卫生—环境卫生学]