子宫内膜微生态与不孕症及IVF-ET结局的相关性研究  

Correlation between endometrial microecology and infertility and IVF-ET outcome

作　　者：卜晓萌 贾婵维[1] 王树玉[1] BU Xiaomeng;JIA Chanwei;WANG Shuyu(Department of Reproductive Medicine,Beijing Gynaecology and Obstetrics Hospital,Capital Medical University,Beijing 100026,China)

机构地区：[1]首都医科大学附属北京妇产医院生殖医学科,北京100026

出　　处：《中国优生与遗传杂志》2021年第4期590-592,共3页Chinese Journal of Birth Health & Heredity

摘　　要：不孕症的病因众多,目前尚有部分病因未明确,给不孕症的诊断及治疗带来困难。随着对微生态认识的加深和测序技术的发展,现在人类逐渐认识到子宫内膜微生物群与子宫内膜容受性之间存在相关性,并可能对女性的妊娠产生影响。体外受精-胚胎移植(IVF-ET)是临床上常用的治疗不孕症的手段,在IVF-ET治疗过程中子宫内膜微生态的差异性表现会对助孕结局产生影响,目前具体机制尚未阐明。本文对以上问题进行文献复习及综述,以期为不孕女性的临床治疗提供新的方法及思路。There are many causes of infertility,and some of them are still unclear,which brings difficulties to the diagnosis and treatment of infertility.With the deepening understanding of micro-ecology and the development of sequencing technology,it is now gradually recognized that there is a correlation between endometrial micro-flora and endometrial receptivity,and it may affect the pregnancy of women.In vitro fertilization and embryo transplantation(IVF-ET)is a commonly used clinical treatment of infertility.The differential expression of endometrial micro-ecology will affect the pregnancy outcome during the treatment of IVF-ET.The specific mechanism has not yet been elucidated.In this paper,the above issues were reviewed and summarized in order to provide new methods and ideas for the clinical treatment of infertile women.

关 键 词：子宫内膜微生态 不孕症 体外受精-胚胎移植 

分 类 号：R711.6[医药卫生—妇产科学]