职业辐射接触与慢性代谢性疾病风险相关性研究  

A study on the correlation between occupational radiation exposure and risk of chronic metoblis disease

作　　者：李遥敏 胡志华 危静[1] 曹承建[2] 褚彦明 杨德业[1] 谢巧英[2] Li Yaomin;Hu Zhihua;Wei Jing;Cao Chengjian;Chu Yanming;Yang Deye;Xie Qiaoying(The Affiliated Hospital of Hangzhou Normal University,Hangzhou 310015,China;HangZhou Hospital for the Prevention and Treatment of Occupational Disease,Hangzhou 310014,China;ZheJiang Elderly Care Hospital,Hangzhou 310000,China)

机构地区：[1]杭州师范大学附属医院,310015 [2]杭州市职业病防治院,310014 [3]浙江老年关怀医院,杭州310000

出　　处：《中华劳动卫生职业病杂志》2021年第9期653-656,共4页Chinese Journal of Industrial Hygiene and Occupational Diseases

基　　金：浙江省自然科学基金重点项目(LZ16H020003);杭州市医疗卫生科研项目(20140633 B32)。

摘　　要：目的探讨职业辐射接触与慢性代谢性疾病的相关性。方法于2020年3月,以整群抽样方法选择杭州市5所医院的医务人员作为研究对象,共572人。按是否接触电离辐射分为暴露组和非暴露组,另随机抽取同期同院体检的普通体检人员99人作为对照组;其中暴露组按辐射接触工龄分为<5年、5~10年、≥10年组。比较各组慢性代谢性疾病、糖尿病和代谢综合征的患病情况,采用二元logistic回归分析研究慢性代谢性疾病与辐射接触时间的相关性。结果随着辐射接触工龄延长,男性晶状体浑浊、胆囊结石、代谢综合征的患病率升高(P<0.05);女性胆囊息肉的患病率升高(P<0.05)。logistic回归模型在调整了体重指数、年龄因素后,辐射接触工龄≥10年是FBG升高的独立危险因素(OR=3.052,P<0.05)。调整性别、年龄因素后,辐射接触工龄是MS的独立危险因素(OR=4.132,P<0.05)。结论长期电离辐射接触会增加慢性代谢性疾病患病风险。Objective To study the correlation between occupational radiation exposure and chronic metabolic diseases.Methods The status of chronic metabolic diseases of medical workers were compared in 5 hospitals in Hangzhou.As representatives of chronic metabolic diseases,diabetes and metabolic syndrome(MS)were compared in association with duration of radiation exposure.Results Long-term ionizing radiation(IR)exposure was led to increased blood pressure,fasting blood glucose(FBG),dyslipidemia,gallbladder disease,and MS.The years of radiation exposure was associated with lens opacity,gallstone and MS in men and gallbladder polyps in women.Radiation working more than 10 years is one of the independent risk factors for increased FBG and MS.Moreover,the risk of FBG increase in the group of radiation working more than 10 years was 3.052 times of that the non-exposed group,and the risk of MS occurrence was 4.132 times that of the non-exposed group.Conclusion Long-term exposure to IR increases the risk of chronic metabolic diseases.

关 键 词：辐射 电离 职业暴露 营养和代谢性疾病 放射工作人员 

分 类 号：R135[医药卫生—劳动卫生]