以多浆膜腔积液和肾损害为突出表现的Castleman病一例  

Castleman disease presenting with polyserositis and renal impairment:a case report

作　　者：周云灿 张路[2] 徐娜[1] 贾丛伟[3] 黄晓明[1] 曾学军[1] Zhou Yuncan;Zhang Lu;Xu Na;Jia Congwei;Huang Xiaoming;Zeng Xuejun(Department of General Practice/General Internal Medicine,Peking Union Medical College Hospital,Peking Union Medical College,Chinese Academy of Medical Sciences,Beijing 100730,China;Department of Hematology,Peking Union Medical College Hospital,Peking Union Medical College,Chinese Academy of Medical Sciences,Beijing 100730,China;Department of Pathology,Peking Union Medical College Hospital,Peking Union Medical College,Chinese Academy of Medical Sciences,Beijing 100730,China)

机构地区：[1]中国医学科学院,北京协和医学院,北京协和医院全科医学科(普通内科),100730 [2]中国医学科学院,北京协和医学院,北京协和医院血液内科,100730 [3]中国医学科学院,北京协和医学院,北京协和医院病理科,100730

出　　处：《中华内科杂志》2021年第10期915-917,共3页Chinese Journal of Internal Medicine

摘　　要：Castleman病是一种较为少见的淋巴组织增生性疾病。本文报道了一例以发热、多浆膜腔积液、肾损害为突出表现的患者,体检发现颈部淋巴结肿大,颈部淋巴结活检病理诊断透明血管型Castleman病,予BCD方案化疗(每28天1个疗程,硼替佐米2.0 mg皮下注射+环磷酰胺450 mg口服+地塞米松40 mg口服,第1、8、15、22天),患者症状缓解,病情稳定出院。对不明原因的多浆膜腔积液患者,应将Castleman病作为鉴别诊断之一。浅表淋巴结部位的细致体检可能有助于提供诊断线索。

关 键 词：CASTLEMAN病 多浆膜腔积液 肾损害 

分 类 号：R551.2[医药卫生—血液循环系统疾病]