Research progress on mechanism of Chinese material medica in preventing and treating insulin resistance and type 2 diabetes mellitus  

作　　者：Jianglan Long Dan Yan 

机构地区：[1]Beijing Institute of Clinical Pharmacy,Beijing Friendship Hospital,Capital Medical University,Beijing,100050,China

出　　处：《TMR Modern Herbal Medicine》2021年第4期1-14,共14页TMR现代中药

摘　　要：Insulin resistance(IR)is a significant feature and one of the basic links in the pathogenesis of type 2 diabetes mellitus(T2DM).Chinese material medica(CMM)has promoted the development of traditional Chinese medicine due to its definite clinical efficacy in the treatment of IR and T2DM.However,owing to the fact that the mechanism of CMM is characterized by“multiple components and multiple targets”,which has not been effectively interpreted,result in the scientificity of clinical efficacy with CMM is controversial.Therefore,this article summarized the mechanisms of CMM and its main active components in improving IR and preventing and treating T2DM,whose aim is to provide valuable reference for the research mechanism on the treatment of IR and T2DM.

关 键 词：Chinese material medica Active components Insulin resistance Type 2 diabetes mellitus Mechanism of action 

分 类 号：R58[医药卫生—内分泌]