1-芳基-3-苯甲酰基-2,5-二苯基吡咯的合成及其性质  

Synthesis and Properties of 1-Aryl-3-Benzoyl-2,5-Diphenyl Pyrrole

作　　者：李葆[1] 张振礼 Li Bao;Zhang Zhenli(Department of Chemistry,Jilin Teacher’s College,Jilin)

机构地区：[1]吉林师范学院化学系

出　　处：《高等学校化学学报》1985年第10期917-918,共2页Chemical Journal of Chinese Universities

摘　　要：文献报导[1],1-芳基-2,5-二甲基3-醛基吡咯和3-亚氩烃甲基吡咯,具有降血压效应。我们曾报导1-芳基-2-甲基-3-乙酰基-5-对氯苯基吡咯和1-芳基-2-甲基-3-乙酰基-5-间硝基吡咯化合物。1-取代-2,5-二苯基吡咯具有止痛作用。Dibenzoylmcthanc was treated with ω-bromoacetophenone to give 1,4-diphenyl -2-benzoyl-1,4-butandionc(1). Eight new 1-aryl-2,5-diphenyl-3-benzoyl pyrroles (2)-(9) were obtained by reactions of (1) with various primary aromatic amines. Semicarbazoncs (10)-(17) were prepared form (2)-(9). Compounds from (1)-(17) were reported for the first time.

关 键 词：苯甲酰基 芳基 止痛作用 吡咯 文献报导 乙酰基 

分 类 号：O62[理学—有机化学]