手征性硫代磷酸及其衍生物的研究(Ⅰ)——O-乙基-O-苯基硫代磷酸的拆分及其手征性硫(醇)代酯的合成  

STUDIES ON CHIRAL THIOPHOSPHORIC ACIDS AND THEIR DERIVATIVES-I——THE RESOLUTION OF O-ETHYL-O-PHENYL PHOSPHOROTHIOIC ACID AND THE SYNTHESIS OF ITS CHIRAL THIOL-ESTERS

作　　者：唐除痴[1] 吴桂萍[1] 柴有新[1] Tang Chuchi;Wu Guiping;Chai Youxin(Institute of Elemento-Organic Chemistry,Nankai University,Tianjin)

机构地区：[1]南开大学元素有机化学研究所

出　　处：《高等学校化学学报》1981年第1期70-76,共7页Chemical Journal of Chinese Universities

摘　　要：以奎宁为拆分剂,在甲醇溶液中,将O-乙基-O-苯基硫代磷酸(Ⅰ)拆分成一对对映异构体■。旋光活性的酸在醇钠存在下与卤代烷反应,得到O-乙基-O-苯基-S-烷基硫代磷酸酯(Ⅱ)的对映异构体■。其中Ⅱ-b和Ⅱ-c两对对映异构体为杀虫剂。Through quinine salt O-ethyl-O-phenyl phosphorothioic acid(I)has been successfully resolved in methanol solution:■The enantiomers of the acid,on reacting with alkyl halides,RX,in the presence of sodium alcoholate,yielded the enantiomers of O-ethyl-O-phenyl-S-alkyl phosphorothioate(Ⅱ):■whereOf these,the two pairsⅡ-b andⅡ-c are insecticides.

关 键 词：对映异构体 硫代磷酸 (Ⅱ) 卤代烷 甲醇溶液 旋光活性 拆分剂 

分 类 号：O62[理学—有机化学]