薄层色谱法分离烷基芳基酮肟立体异构体  

An Investigation in Separation of the Geometric Isomers of Alkyl Aryl Ketone Oxime by TLC

作　　者：龙韫先[1] 叶春芝[1] 黄润秋[1] Long Yunxian;Ye Chunzhi;Huang Runqiu(The Institute of Elemento-Organic Chemistry,Nankai University,Tianjin)

机构地区：[1]南开大学元素有机化学研究所

出　　处：《高等学校化学学报》1988年第9期963-965,共3页Chemical Journal of Chinese Universities

摘　　要：我们对酮肟中间体及肟醚类拟除虫菊酯进行了分析。经核磁共振证明,酮肟中间体在生成肟醚南反应过程中其立体构型木发生变化。目前分离酮肟立体异构物的工作报道较少。我们通过薄层色谱对不同取代的具有活性的几种酮肟异构体的分离进行了探讨。The TLC separation of the geometric isomers of alkyl aryl ketone oximes which are the intermediates in the synthesis of a new group of pyrethroidlike alkylaryl ketone oxime o-ethers (the general structure ishas been investigated. The optimal conditions and the results for the E/Z separation of six different substituted phenyl isopropyl ketone oximes are given. The dependence of the three thin layer chromatographic parameters, R f, ΔR f and α, on varying ratio of the TLC mobile phase ha been studied and the effect of the activity of absorbent on the separation is discussed.

关 键 词：E/Z异构体 酮肟 分离 薄层色谱 

分 类 号：TQ4[化学工程]