磁共振成像技术在强迫症重复经颅磁刺激效果评估中的价值研究进展  

Research progress on the value of magnetic resonance imaging technique in evaluating the efficacy of repetitive transcranial magnetic stimulation in patients with obsessive-compulsive disorder

作　　者：刘肖肖 杨克硕 白岩 王梅云 陈传亮 LIU Xiaoxiao;YANG Keshuo;BAI Yan;WANG Meiyun;CHEN Chuanliang(Department of Medical Imaging,People's Hospital of Henan University,Henan Provincial People's Hospital,Zhengzhou 450003,China;Department of Medical Imaging,Zhengzhou University People's Hospital,Zhengzhou 450003,China)

机构地区：[1]河南大学人民医院,河南省人民医院影像科,郑州450003 [2]郑州大学人民医院影像科,郑州450003

出　　处：《磁共振成像》2021年第10期82-84,共3页Chinese Journal of Magnetic Resonance Imaging

基　　金：国家重点研发计划项目(编号:2017YFE0103600);国家自然科学基金项目(编号:81720108021)。

摘　　要：目前,针对强迫症的常用治疗方法包括药物治疗、心理治疗和外科手术治疗等,但效果欠佳,仍有一部分患者在治疗后出现强迫症状。重复经颅磁刺激作为一种新兴的无创治疗手段,通过改变脉冲的频率,利用电磁场来调节大脑皮层的活动,从而改善强迫症患者的症状。但在刺激靶点的选择、参数设置等方面尚需进一步深入探讨。本文对重复经颅磁刺激治疗强迫症方面的研究进展进行综述,总结刺激不同靶点产生的临床疗效以及磁共振成像技术在强迫症经重复颅磁刺激治疗效果评估中的价值。At present,the common treatment for obsessive-compulsive disorder(OCD)includes drug therapy,psychological therapy and surgical treatment,but the effect is not good,and some patients still have OCD symptoms after treatment.As a new non-invasive treatment,repetitive transcranial magnetic stimulation(rTMS)can improve the symptoms of OCD patients by changing the frequency of pulse and using electromagnetic field to regulate the activity of cerebral cortex.But the choice of stimulation target and parameter setting need to be further discussed.This article reviews the research progress of rTMS in the treatment of OCD,to summarize the clinical efficacy of stimulation of different targets and the value of magnetic resonance imagin technique in evaluating the efficacy of rTMS for OCD.

关 键 词：强迫症 重复经颅磁刺激 磁共振成像 机制 神经导航技术 

分 类 号：R445.2[医药卫生—影像医学与核医学] R749.79[医药卫生—诊断学]