印度尼西亚儿童牛奶摄入与乳糖吸收不良之间的关系  

Association between milk consumption and lactose malabsorption in Indonesian children

作　　者：Syarimonitha Munadzilah Badriul Hegar Rini Sekartini Yvan Vandenplas 

机构地区：[1]Department of Child Health,Faculty of Medicine Universitas Indonesia,Dr.Cipto Mangunkusumo Hospital Jakarta,Indonesia [2]Kidz Health Castle,UZ Brussel,Vrije Universiteit Brussel,Brussels,Belgium

出　　处：《中国当代儿科杂志》2021年第10期975-980,共6页Chinese Journal of Contemporary Pediatrics

摘　　要：目的探讨3~12岁印度尼西亚儿童牛奶摄入与乳糖吸收不良之间的关系。方法该研究为横断面研究。研究对象为在印度尼西亚雅加达中部随机选取的营养状况良好的174名3~12岁健康儿童,包括72名3~5岁儿童和102名6~12岁儿童。结果3~5岁儿童乳糖吸收不良患病率为20.8%(15/72),6~12岁儿童乳糖吸收不良患病率为35.3%(36/102)。牛奶或乳制品摄入与乳糖吸收不良之间无显著关联性(P>0.05)。在氢呼气试验中,51例乳糖吸收不良儿童主要表现为腹泻(62%)、腹痛(52%)和恶心(5%)。结论3~12岁印度尼西亚儿童牛奶摄入和乳糖吸收不良无关联,这提示遗传易感性可能比乳糖摄入的适应机制更重要。Objective To study the association between milk consumption and lactose malabsorption in Indonesian children aged 3-12 years.Methods This cross sectional study was conducted in randomly selected presumed healthy children with good nutritional status aged 3-12 years in Central Jakarta,Indonesia(n=174),including 72 children aged 3-5 years and 102 children aged 6-12 years.Results The prevalence of lactose malabsorption in children aged 3-5 years and children aged 6-12 years was 20.8%(15/72)and 35.3%(36/102),respectively.There was no association between milk or milk product consumption and lactose malabsorption(P>0.05).In the 51 children with lactose malabsorption,the predominant clinical symptoms were diarrhea(62%),abdominal pain(52%),and nausea(5%)during the hydrogen breath test.Conclusions There is no association between milk consumption and lactose malabsorption in Indonesian children aged 3-12 years,suggesting that genetic predisposition may be more important than adaptive mechanisms to lactose consumption.

关 键 词：乳糖吸收不良 氢呼气试验 牛奶摄入 患病率 儿童 

分 类 号：R723.1[医药卫生—儿科]