锥光束乳腺CT在三阴型乳腺癌新辅助化疗中的疗效评价  

Evaluation of Cone Beam Breast CT in Neoadjuvant Chemotherapy for Triple Negative Breast Cancer

作　　者：杨巧鹭[1] 饶明月[2] 郑碧玉[3] YANG Qiaolu;RAO Mingyue;ZHENG Biyu(Department of Breast Surgery,The First Affiliated Hospital of Xiamen University,Xiamen Fujian 361003,China;Department of Radiology,The First Affiliated Hospital of Xiamen University,Xiamen Fujian 361003,China;Department of Ultrasonography,The First Affiliated Hospital of Xiamen University,Xiamen Fujian 361003,China)

机构地区：[1]厦门大学附属第一医院乳腺外科,福建厦门361003 [2]厦门大学附属第一医院放射影像科,福建厦门361003 [3]厦门大学附属第一医院超声科,福建厦门361003

出　　处：《中国卫生标准管理》2021年第19期73-76,共4页China Health Standard Management

摘　　要：目的分析锥光束乳腺CT(cone beam breast computed tomography,CBBCT)在三阴型乳腺癌新辅助化疗疗效评价的应用。方法选取2019年6月—2020年6月科室收治的三阴型乳腺癌女性患者共56例。所有患者均采取术前新辅助化疗,化疗完成后均接受乳腺癌改良根治术。在第一次新辅助化疗前及手术前两个时间节点对患者分别采用临床触诊、彩色多普勒超声、CBBCT进行评估,对比3种方法与“金标准”术后病理的一致性。结果56例患者术后病理评估总体有效率为66.07%(37/56)。触诊评价有效率为50.00%(28/56),一致性为0.32;超声评价有效率为58.93%(33/56),一致性为0.62;CBBCT评价有效率为62.50%(35/56);一致性为0.77。新辅助疗效评价两两之间差异无统计学意义(P>0.05),但与术后病理的一致性比较两两间差异有统计学意义(P<0.05)。结论CBBCT作为一种新型的检查方法,对乳腺癌新辅助化疗疗效的评估相比触诊、超声更加准确,具有一定临床应用意义。Objective To analyze the application of cone beam breast computed tomography(CBBCT)in the evaluation of neoadjuvant chemotherapy for triple negative breast cancer.Methods A total of 56 female patients with triple-negative breast cancer admitted to our hospital from June 2019 to June 2020 were selected.All patients received preoperative neoadjuvant chemotherapy and underwent modified radical mastectomy after chemotherapy.At two time points before the first neoadjuvant chemotherapy and before the operation,the patients were examined by clinical palpation measurement,color Doppler ultrasound and CBBCT respectively,and the consistency between the three results of the three examination methods and the"gold standard"the pathological results after surgery was compared.Results The total effective rate of 56 patients after neoadjuvant chemotherapy was 66.07%(37/56).The effective rate of palpation evaluation was 50.00%(28/56),and the consistency was 0.32.The effective rate of ultrasonic examination evaluation was 58.93%(33/56),and the consistency was 0.62.The effective rate of CBBCT was 62.50%(35/56).The consistency was 0.77.There was no statistically significant difference in neoadjuvant efficacy between the two groups(P>0.05),but the comparison of consistency with postoperative pathological results showed statistically significant difference between the two groups(P<0.05).Conclusion As a new examination method,CBBCT is more accurate than palpation and ultrasound in evaluating the efficacy of neoadjuvant chemotherapy for breast cancer,which has certain clinical application significance.

关 键 词：锥光束乳腺CT 彩色多普勒超声 临床触诊 新辅助化疗 三阴型乳腺癌 疗效评价 

分 类 号：R445[医药卫生—影像医学与核医学]