补肾活血通络法治疗薄型子宫内膜肾虚血瘀证临床疗效观察  

Kidney-tonifying blood-activating collateral-unblocking method for thin endometrium of the kidney deficiency and blood stasis pattern

作　　者：贾静 李云波 马小娜 郝秀芳 申萌萌 王峥 和翔宇 Jia Jing;Li Yunbo#;Ma Xiaona;Hao Xiufang;Shen Mengmeng;Wang Zheng;He Xiangyu(Department of Gynecology,Beijing University of Chinese Medicine Third Affiliated Hospital,Beijing 100029)

机构地区：[1]北京中医药大学第三附属医院妇科,北京100029

出　　处：《现代中医临床》2021年第5期14-19,共6页Modern Chinese Clinical Medicine

基　　金：中央高校基本科研业务费专项资金资助(No.2019-JYB-JS-168)。

摘　　要：目的观察补肾活血通络法治疗薄型子宫内膜肾虚血瘀证的临床疗效。方法选取68例薄型子宫内膜患者,采用随机数字表法将入组患者随机分为治疗组34例、对照组34例。剔除脱落病例后,治疗组30例、对照组30例。治疗组予补肾活血通络方加减治疗,对照组予口服戊酸雌二醇加黄体酮胶囊治疗。观察子宫内膜厚度、子宫内膜类型、子宫内膜血流类型、子宫内膜血流阻力指数(RI)和搏动指数(PI)值、子宫动脉RI和PI值、中医症状评分。结果治疗后2组子宫内膜厚度均较治疗前增厚,差异均有统计学意义(P<0.05)。治疗后治疗组A型内膜比例高于对照组、C型内膜比例低于对照组,差异均有统计学意义(P<0.05),治疗组优于对照组。治疗后2组子宫内膜血流类型均较治疗前改善(P<0.05),治疗组优于对照组,差异均有统计学意义(P<0.05)。治疗后,治疗组患者子宫内膜血流RI,PI较治疗前降低(P<0.05),治疗后2组患者子宫动脉血流RI,PI较治疗前降低(P<0.05)。治疗后2组月经量、行经时间评分较本组治疗前均降低,差异均有统计学意义(P<0.05)。治疗后,治疗组月经色质、腰膝酸软、头晕耳鸣、行经腹痛评分较本组治疗前均降低,差异均有统计学意义(P<0.05)。治疗后,治疗组各症状及总积分较对照组降低明显,治疗前后症状评分差值比较,差异均有统计学意义(P<0.05)。结论补肾活血通络法治疗薄型子宫内膜肾虚血瘀证具有较好的临床效果。Objective To observe the clinical efficacy of kidney-tonifying blood-activating collateral-unblocking method for thin endometrium of the kidney deficiency and blood stasis pattern.Methods Sixty-eight patients with thin endometrium were randomly assigned to the treatment group(34 cases)and the control group(34 cases).With the withdrawal and drop-outs excluded,there were 30 cases in the treatment group and 30 cases in the control group.The treatment group was treated with modified Bushen Huoxue Tongluo Decoction,and the control group was treated with Estradiol Valerate and Progesterone Capsule.Endometrial thickness,endometrial type,endometrial blood flow type,resistant index(RI)and pulse index(PI)value of endometrial blood flow,RI and PI value of uterine artery and TCM symptom score were observed.Results The endometrial thickness was thicker after treatment than before treatment in both groups,and the differences were statistically significant(P<0.05).After treatment,the proportion of type A endometrium was higher in the treatment group than in the control group,and the proportion of type C endometrium was lower in the treatment group than in the control group,and the differences were statistically significant(P<0.05).After treatment,the endometrial blood flow types of the two groups were improved,as compared with those before treatment(P<0.05),better in the treatment group than in the control group,and the differences were statistically significant(P<0.05).RI and PI of endometrial blood flow in the treatment group were lower after treatment,than before treatment(P<0.05),and RI and PI of uterine artery blood flow in the two groups were lower than before treatment(P<0.05).The menstrual volume and menstrual time scores were lower after treatment than before treatment in both groups,and the differences were statistically significant(P<0.05).In the treatment group,the scores of menstrual color,waist and knee soreness,dizziness,tinnitus and abdominal pain were lower after treatment than before treatment,and the differen

关 键 词：补肾活血通络法 薄型子宫内膜 肾虚血瘀证 临床疗效 

分 类 号：R271.9[医药卫生—中西医结合]