腹腔镜治疗胰腺体尾部占位性病变的效果  

Effect of laparoscopy in the treatment of space-occupying lesions in the body and tail of the pancreas

作　　者：付强[1] FU Qiang(Department of Hepatobiliary and Pancreatic Surgery,Jilin People’s Hospital,Changchun 130021,China)

机构地区：[1]吉林省人民医院肝胆胰外科,130021

出　　处：《中国实用医药》2021年第29期47-49,共3页China Practical Medicine

摘　　要：目的分析腹腔镜治疗胰腺体尾部占位性病变的效果。方法82例胰腺体尾部占位性病变患者,采用奇偶数法分为参照组及治疗组,每组41例。参照组实施传统开腹术治疗,治疗组实施腹腔镜胰体尾切除术治疗。比较两组患者的临床指标(术中出血量、首次排气时间、术后进食时间、住院时间),手术前后的应激反应指标[皮质醇、空腹胰岛素、肿瘤坏死因子-α(TNF-α)、空腹血糖]。结果治疗组患者的术中出血量(98.34±8.25)ml少于参照组的(116.47±9.66)ml,首次排气时间(2.58±0.33)d、术后进食时间(4.12±1.50)d、住院时间(12.34±1.50)d短于参照组的(4.16±0.73)、(6.85±2.11)、(16.85±1.80)d,差异具有统计学意义(P<0.05)。手术后,两组患者的皮质醇、空腹胰岛素、TNF-α、空腹血糖水平均高于本组手术前,但治疗组患者的皮质醇、空腹胰岛素、TNF-α、空腹血糖水平低于参照组,差异具有统计学意义(P<0.05)。结论腹腔镜胰体尾切除术用于胰腺体尾部占位性病变的治疗效果理想,对于临床指标和手术应激反应的改善具有促进作用,临床可进一步推广运用。Objective To analyze the effect of laparoscopy in the treatment of space-occupying lesions in the body and tail of the pancreas.Methods A total of 82 patients with space-occupying lesions in the body and tail of the pancreas were divided in to reference group and treatment group according to odd-even number method,with 41 cases in each group.The reference group was treated with traditional laparotomy,and the treatment group was treated with laparoscopic pancreatic body and tail resection.Patients in both groups were compared in terms of clinical indicators(intraoperative blood loss,first exhaust time,postoperative eating time,hospitalization time),stress response indicators[cortisol,fasting insulin,tumor necrosis factor-α(TNF-α),fasting blood glucose]before and after surgery.Results The intraoperative blood loss(98.34±8.25)ml of the treatment group was less than(116.47±9.66)ml of the reference group,and the first exhaust time(2.58±0.33)d,postoperative eating time(4.12±1.50)d and hospitalization time(12.34±1.50)d were shorter than(4.16±0.73),(6.85±2.11)and(16.85±1.80)d of the reference group.All the differences were statistically significant(P<0.05).After surgery,the cortisol,fasting insulin,TNF-αand fasting blood glucose levels in both groups were higher than those before surgery in this group,but the cortisol,fasting insulin,TNF-αand fasting glucose levels in the treatment group were lower than those in the reference group.All the differences were statistically significant(P<0.05).Conclusion Laparoscopic pancreatic body and tail resection has ideal effect on space-occupying lesions in the body and tail of the pancreas,and it has a promoting effect on the improvement of clinical indicators and surgical stress response.So it can be further promoted and applied in clinic.

关 键 词：胰腺体尾部占位性病变 腹腔镜胰体尾切除术 临床指标 手术应激反应 

分 类 号：R657.5[医药卫生—外科学]