2014~2018年福州市新增艾滋病患者抗病毒治疗情况分析  

Analysis on characteristics of AIDS patients receiving antiretroviral therapy,Fuzhou city,2014-2018

作　　者：林春仲 张宏[1] 许绍溢[1] 何鼎盛 刘梅艳[1] 陈传刚[1] LIN Chun-zhong;ZHANG Hong;XU Shao-yi;HE Ding-sheng;LIU Mei-yan;CHEN Chuan-gang(Fuzhou City Center for Disease Control and Prevention,Fuzhou,Fujian,350004,China;不详)

机构地区：[1]福州市疾病预防控制中心,福建福州350004

出　　处：《预防医学论坛》2021年第9期687-690,共4页Preventive Medicine Tribune

摘　　要：目的了解第三轮全国艾滋病示范区期间福州市新增抗病毒治疗病人治疗用药情况与特征,为进一步制定福州市艾滋病抗病毒治疗的相关措施与新确诊病例行为学干预指导提供参考依据。方法以2014~2018年现住址为福州市的新增治疗的1902例艾滋病确诊病例为研究对象,对其相关治疗信息建立数据库并进行统计分析。结果2014~2018年福州市艾滋病抗病毒新增治疗病人1902例,年龄为(39.11±14.48)岁,男性平均年龄(38.34±15.54)较女性(44.85±13.42)低(P<0.01),男女比例为7.38∶1;女性婚姻情况为已婚或同居高于男性,男性主要为未婚为主,差异有统计学意义(P<0.01);新增治疗病例中男性以临床Ⅲ期为主,占50.93%(853/1676),女性以Ⅱ期为主,占43.81%(99/226);首次检测CD4+T淋巴细胞检测率93.74%(1783/1902),均值为(252.38±189.62)个/μl;从确诊感染至接受抗病毒治疗经历了(19.15±34.08)周;确诊年龄在不同确诊年份中差异有统计学意义(P<0.01),在不同确诊年份间的"确诊-治疗"等待时间差异有统计学意义(P<0.01);2018年晚发现率44.50%较2014年晚发现率45.75%有所下降,2018年早发现率(12.88%)高于2014年(4.25%)(P<0.01)。各年新增治疗病例在临床分期上差异无统计学意义(P>0.05)。结论2014~2018年福州市新增艾滋病感染者以男性为主,"确证-接受治疗"周期逐年缩短,早发现率有所提升。Objective To understand the situation and characteristics of antiviral treatment in Fuzhou city during the third round of national AIDS demonstration zone,so as to provide reference for further formulating relevant measures of anti viral treatment and behavioral intervention guidance of newly diagnosed cases in Fuzhou city.Methods A database of 1902 AIDS newly diagnosed cases with current address in Fuzhou city from 2014 to 2018 was established and analyzed based on the treatment information.Results From 2014 to 2018,there were 1902 new HIV/AIDS patients in Fuzhou city,with an average age of(39.11±14.48)years.The average age of male(38.34±15.54)was lower than that of female(44.85±13.42)(P<0.01),and the ratio of male to female was 7.38:1;the marriage status of women who were married or cohabited was higher than that of men who were unmarried(P<0.01).In the new treatment cases,the male patients were mainly in clinical stageⅢ,accounting for 50.93%(853/1676),and the female patients were mainly in stageⅡ,accounting for 43.81%(99/226).The detection rate of CD4+T lymphocytes in the first test was 93.74%(1783/1902),with the average value of(252.38±189.62)cells/μl;(19.15±34.08)weeks from the date of infection diagnosis to the date of receiving antiviral therapy;the difference in the age of definite diagnosis was statistically significant in different years of definite diagnosis(P<0.01),and the waiting time for"definite diagnosis-treatment"between different years of definite diagnosis was statistically significant(P<0.01).The late detection rate of 44.50%in 2018 was lower than that of 45.75%in 2014,and the early detection rate of 12.88%in 2018 was higher than 4.25%in 2014(P<0.01).There was no significant difference in clinical stages of newly added cases between years(P>0.05).Conclusion From 2014 to 2018,the majority of new AIDS cases in Fuzhou city were male,the cycle of"confirmation-treatment"shortened year by year,and the rate of early detection increased.

关 键 词：抗病毒治疗 艾滋病 CD4+T淋巴细胞 晚发现率 第三轮示范区 

分 类 号：R512.91[医药卫生—内科学]