“大接经”针刺联合低频重复经颅磁刺激治疗对失眠患者睡眠质量及神经递质的影响  

Efficacy Evaluation of“Findout the Original Winding with Acupuncture Point Method”Combined with Low-frequency Repetitive Transcranial Magnetic Stimulation on Sleep Quality and Neurotransmitters in Patients with Insomnia

作　　者：张胜男[1] ZHANG Shengnan(Dalian Municipal Central Hispital,Dalian 116033,China)

机构地区：[1]辽宁省大连市中心医院,辽宁大连116033

出　　处：《中国医学创新》2021年第27期78-81,共4页Medical Innovation of China

摘　　要：目的:探究"大接经"针刺联合低频重复经颅磁刺激(Lf-rTMS)治疗对失眠患者睡眠质量及神经递质的影响。方法:选取2018年6月-2021年2月85例经大连市中心医院治疗且确诊为心肾不交型失眠症患者,根据随机数字表法将其分为对照组(n=42)和观察组(n=43)。对照组采用常规体针针刺联合Lf-rTMS,观察组采用大接经针刺联合Lf-rTMS治疗。比较两组治疗前后的中医证型评分量表(TCMSS)、匹兹堡睡眠质量指数量表(PSQI)、血清氨基酸类神经递质谷氨酸(Glu)和γ-氨基丁酸(GABA)水平。结果:治疗前,两组TCMSS、PSQI评分比较,差异均无统计学意义(P>0.05);治疗后,两组TCMSS、PSQI评分均低于治疗前,且观察组均低于对照组,差异均有统计学意义(P<0.05)。治疗前,两组Glu、GABA比较,差异均无统计学意义(P>0.05);治疗后,两组Glu均低于治疗前,GABA均高于治疗前,且观察组Glu低于对照组,GABA高于对照组,差异均有统计学意义(P<0.05)。结论:大接经针刺法联合低频重复经颅磁刺激,可有效缓解失眠症状、提高睡眠质量,改善神经递质谷氨酸、γ-氨基丁酸水平,具有临床应用推广价值。Objective:To explore the efficacy of"findout the original winding with acupuncture point method"combined with low-frequency repetitive transcranial magnetic stimulation(Lf-rTMS)on sleep quality and neurotransmitters in patients with insomnia.Method:A total of 85 patients with heart-kidney disconnection insomnia who were treated in Dalian Central Hospital from June 2018 to February 2021 were selected,and they were divided into control group(n=42)and observation group(n=43)according to random number table method.The control group was treated with conventional body acupuncture combined with Lf-rTMS,and the observation group was treated with findout the original winding with acupuncture point method combined with Lf-rTMS.The traditional Chinese medicine syndromes scale(TCMSS),Pittsburgh sleep quality index(PSQI)and serum levels of amino acid neurotransmitters glutamate(Glu)andγ-aminobutyric acid(GABA)before and after treatment were compared between two groups.Result:Before treatment,there were no significant differences in TCMSS and PSQI scores between two groups(P>0.05);after treatment,TCMSS and PSQI scores in both groups were lower than those before treatment,and those in the observation group were lower than those in the control group,the differences were statistically significant(P<0.05).Before treatment,there were no significant differences in Glu and GABA between two groups(P>0.05);after treatment,Glu in both groups were lower than those before treatment,and GABA in both groups were higher than those before treatment,Glu in the observation group was lower than that in the control group,and GABA in the observation group was higher than that in the control group,the differences were statistically significant(P<0.05).Conclusion:Findout the original winding with acupuncture point method combined with low frequency repetitive transcranial magnetic stimulation can effectively relieve insomnia symptoms,improve sleep quality,improve neurotransmitter glutamate,γ-aminobutyric acid levels,which has clinical application

关 键 词：大接经针刺 低频重复经颅磁刺激 失眠 中医证型评分 匹兹堡睡眠质量指数量表 谷氨酸 γ-氨基丁酸 

分 类 号：R246.6[医药卫生—针灸推拿学]