姜黄素抗炎作用在疾病治疗中的研究进展  

Research Progress on Anti-inflammatory Effect of Curcumin in Disease Treatment

作　　者：孙艺洋 彭子熠 赵雨鑫 孔凡博 王慧[1] SUN Yiyang;PENG Ziyi;ZHAO Yuxin;KONG Fanbo;WANG Hui(Qiqihar Medical College,Qiqihar 161006,China;不详)

机构地区：[1]齐齐哈尔医学院,黑龙江齐齐哈尔161006

出　　处：《中国医学创新》2021年第27期181-184,共4页Medical Innovation of China

基　　金：黑龙江省大学生创新创业训练项目(202011230019);黑龙江省教育厅科学技术研究项目(2017-KYYWF-0733)。

摘　　要：姜黄素是一种脂溶性多酚类化合物,是姜黄发挥药理作用的主要成分,是从姜黄的根茎中提取得来的。目前研究发现,姜黄素具有抗炎、抗肿瘤、抗纤维化、抗氧化应激等药理作用。在临床研究中,抗炎治疗一直是重点。近年来对姜黄素抗炎作用的研究越来越受关注,因其强大的抗炎活性被广泛应用于各种炎症相关性疾病的治疗中,如糖尿病肾病、阿尔茨海默病、类风湿性关节炎、非酒精性脂肪肝、动脉粥样硬化、结肠炎等。本文旨在通过归纳姜黄素抗炎作用,为临床上治疗炎症性疾病提供参考。Curcumin is a fat-soluble polyphenol compound.It is the main ingredient in turmeric for its pharmacological effects,which is extracted from the root and stem of turmeric.Current studies have found that curcumin has anti-inflammatory,anti-tumor,anti-fibrosis,anti-oxidative stress and other pharmacological effects.In clinical research,anti-inflammatory treatment has always been the focus.In recent years,the research on curcumin’s anti-inflammatory effect has attracted more and more attention.Because of its strong anti-inflammatory activity,curcumin is widely used in the treatment of various inflammatory related diseases,such as diabetic nephropathy,Alzheimer’s disease,rheumatoid arthritis,non-alcoholic fatty liver disease,atherosclerosis,colitis and so on.This paper aims to summarize the anti-inflammatory effect of curcumin and provide reference for the clinical treatment of inflammatory diseases.

关 键 词：姜黄素 抗炎作用 糖尿病肾病 阿尔茨海默病 类风湿性关节炎 

分 类 号：R285.5[医药卫生—中药学]