脓毒症患者预后的影响因素分析  

Analysis of Factors Influencing the Prognosis of Patients with Sepsis

作　　者：程坤 余广炜[3] 赵力澜 薛贻敏[1,2] CHEGN Kun;YU Guangwei;ZHAO Lilan;XUE Yimin(Fujian Provincial Hospital,Fuzhou 350001,China;不详)

机构地区：[1]福建省立医院,福建福州350001 [2]福建医科大学省立临床医学院 [3]福建医科大学附属协和医院

出　　处：《中国医学创新》2021年第26期1-5,共5页Medical Innovation of China

基　　金：福建省重症医学中心建设项目(2017-510);福建省卫生健康科研人才培养项目(2019-2-1)。

摘　　要：目的:探讨影响脓毒症患者预后的因素。方法:回顾性分析2013年1月-2019年12月福建省立医院重症医学四科及福建医科大学附属协和医院急诊监护室(统称ICU)495例脓毒症患者的临床资料。根据在院临床结局,将患者分为死亡组(n=204)和存活组(n=291)。采用多因素logistic回归分析影响预后的独立危险因素。结果:两组E、e’、血小板计数、肌酐最高值、SOFA评分、ICU住院时间、心功能分级、腹腔感染、机械通气、2型糖尿病、冠心病比较,差异均有统计学意义(P<0.05)。多因素分析结果显示,E、血小板计数、ICU住院天数、腹腔感染、机械通气、2型糖尿病、冠心病是影响脓毒症患者死亡的独立影响因素(P<0.05)。结论:E、血小板计数、ICU住院时间、机械通气、腹腔感染、合并冠心病、2型糖尿病是影响脓毒症患者预后的独立因素。Objective:To explore the factors affecting the prognosis of patients with sepsis.Method:Clinical data of 495 patients with sepsis in the fourth department of Critical Care Medicine of Fujian Provincial Hospital and the Emergency Care Unit of Union Hospital affiliated to Fujian Medical University(general ICU)from January 2013 to December 2019 were retrospectively analyzed.According to the clinical outcome in hospital,the patients were divided into death group(n=204)and survival group(n=291).Multivariate logistic regression was used to analyze independent risk factors affecting prognosis.Result:Comparison of E,e’,platelet count,maximum creatinine,SOFA score,ICU stay,cardiac function grade,abdominal infection,mechanical ventilation,type 2 diabetes and coronary heart disease between the two groups,the differences were statistically significant(P<0.05).Multivariate analysis showed that E,platelet count,ICU stay,abdominal infection,mechanical ventilation,type 2 diabetes and coronary heart disease were independent factors affecting the death of sepsis patients(P<0.05).Conclusion:E,platelet count,ICU hospitalization time,mechanical ventilation,abdominal infection,coronary heart disease,and type 2 diabetes are independent factors affecting the prognosis of patients with sepsis.

关 键 词：脓毒症 左心室舒张功能障碍 二尖瓣舒张早期血流峰速度 预后 

分 类 号：R459.7[医药卫生—急诊医学]