银屑病并发砷角化病一例  

Psoriasis complicated with arsenate keratosis:a case report

作　　者：王娟娟 尹兴平 孙丽囡 高远 陆晓君[1] 刘伟[1] WANG Juanjuan;YIN Xingping;SUN Linan;GAO Yuan;LU Xiaojun;LIU Wei(Department of Dermatology,People s Hospital of Suzhou New District,Suzhou 215129,China)

机构地区：[1]苏州高新区人民医院皮肤科,江苏苏州215129

出　　处：《中国麻风皮肤病杂志》2022年第1期51-53,共3页China Journal of Leprosy and Skin Diseases

摘　　要：患者,男,19岁。掌跖角化性丘疹、斑片,躯干、上肢近端色素异常1年余。患有银屑病8年,近2年长期服用当地诊所自制中成药丸(具体成分不详)。皮肤科检查:躯干、上肢近端见密集分布的色素沉着斑,中间夹杂色素减退斑,掌跖及侧缘多发角化过度性斑丘疹。砷含量测定:血、尿砷增高,药丸砷含量1.5 mg/100 g。治疗:停服中药丸剂;给予二巯基丙磺酸钠、阿维A胶囊等;皮损处外用维A酸乳膏封包。治疗2个月后掌跖角化性皮疹和躯干色素异常有好转,但头皮、躯干、四肢出现散在鳞屑性红斑。复查血砷、尿砷均恢复至正常水平。A 19-year-old youngster presented with palmplantar keratotic papules and patches,dyspigmentation on the trunk and proximal upper extremities over a year.He had a history of psoriasis vulgaris for 8 years.In the past 2 years,he has been taking some self-made pills(unknown ingredients)by a traditional Chinese medicine practitioner at a local clinic.Hyperpigmented patches mixed with hypopigmented macules were found on the body and proximal upper extremities.Some coalesced into patches with the file-like sensation.The level of arsenic in blood and urine were both elevated.The content of arsenic in self-made pills was 1.5 mg/100 g.The patient was told to stop taking the traditional Chinese medicine pills.The patient was treated with sodium dimercaptopropanesulfonate and acitretin capsules.0.1%tretinoin cream was enclosed on the palms and soles.After 2 months,the palmoplantar hyperkeratosis and the dyspigmentation on the trunk were both markedly improved,but some sparsely-distributed,scaly erythema appeared on the scalp,trunk and extremities appeared.The arsenic content in lood and urine were both normal.

关 键 词：砷角化症 银屑病 

分 类 号：R758.63[医药卫生—皮肤病学与性病学]