肾上腺素自动注射器应用指南解读  

Interpretation of guideline on adrenaline autoinjector application:European Academy of Allergy and Clinical Immunology anaphylaxis guideline(2021 update)

作　　者：高琦[1] 许巍[2] 殷菊[1] 申昆玲[1] Gao Qi;Xu Wei;Yin Ju;Shen Kunling(Department of Respiratory DiseasesⅠ,Beijing Children′s Hospital,Capital Medical University,China National Clinical Research Center for Respiratory Diseases,National Center for Children′s Health,Beijing 100045,China;Department of Allergy,Beijing Children′s Hospital,Capital Medical University,China National Clinical Research Center for Respiratory Diseases,National Center for Children′s Health,Beijing 100045,China)

机构地区：[1]国家儿童医学中心,国家呼吸系统疾病临床医学研究中心,首都医科大学附属北京儿童医院呼吸一科,北京100045 [2]国家儿童医学中心,国家呼吸系统疾病临床医学研究中心,首都医科大学附属北京儿童医院过敏反应科,北京100045

出　　处：《中华实用儿科临床杂志》2021年第18期1373-1376,共4页Chinese Journal of Applied Clinical Pediatrics

基　　金：国家重点研究发展计划(2016YFC0901103)。

摘　　要：严重过敏反应是一种速发、可全身多系统受累并危及生命的超敏反应,肌内注射肾上腺素是一线治疗,肾上腺素自动注射器是急救时重要的给药装置。2021年,欧洲变态反应与临床免疫学会发布的严重过敏反应更新指南中,对肾上腺素自动注射器的应用做了推荐指导,现对该部分内容进行解读,包括肾上腺素自动注射器的优势、处方适应证、药代动力学数据、剂量选择和长期管理等,以期提高儿科医师对肾上腺素自动注射器的认识和未来规范化使用。Anaphylaxis is a hypersensitivity reaction that is rapid in onset,multi-system involved and can be fatal.Adrenaline is the first-line treatment of anaphylaxis.Adrenaline autoinjector is an important device in emergent situation.In European Academy of Allergy and Clinical Immunology anaphylaxis guideline updated in 2021,adrenaline autoinjector is systemically described and recommended.The following interpretation is focused on adrenaline autoinjector,including advantages,indications for prescription,pharmacokinetic data,dose and long-term management,aimed to enhance understanding of this device and standardize future application.

关 键 词：严重过敏反应 肾上腺素 自动注射器 

分 类 号：TH789[机械工程—仪器科学与技术]