一起新型冠状病毒肺炎无症状感染者引起的家庭聚集性疫情分析  

A family clustering of coronavirus disease 2019 caused by asymptomatic infection

作　　者：田竞[1] 李丽丽[1] 李海娇[1] 郭新慧[1] 魏柯雯 马仲慧 阚震[1] 黄少平[1] TIAN Jing;LI Li-li;LI Hai-jiao;GUO Xin-hui;WEI Ke-wen;MA Zhong-hui;KAN Zhen;HUANG Shao-ping(Department for Infectious and Endemic Diseases Control,Fangshan District Center for Disease Control and Prevention,Beijing 102488,China)

机构地区：[1]北京市房山区疾病预防控制中心传染病与地方病控制科,北京102488

出　　处：《上海预防医学》2021年第9期795-799,共5页Shanghai Journal of Preventive Medicine

基　　金：北京市优秀人才培养资助项目(2018000077606G480);北京市房山区优秀人才培养资助项目(2016000000007G002)。

摘　　要：【目的】分析北京市房山区一起新型冠状病毒肺炎无症状感染者引起的家庭聚集性疫情流行病学特征,为针对性控制聚集性疫情扩散提供科学依据。【方法】采用描述性流行病学方法对家庭中1名确诊病例和2名无症状感染者进行流行病学调查,通过实时荧光定量聚合酶链法进行新型冠状病毒核酸检测。【结果】本起疫情发生在一个家庭内,2例无症状感染者B和C为父子关系,均有武汉居住史,2020年1月24日到京后,1名家庭成员(病例A,无症状感染者B的母亲)于2月7日发病,其他2名家庭成员(无症状感染者B的妻子D和哥哥E)均未发病,按密切接触者管理。【结论】无症状感染者是本起家庭聚集性疫情的传染源,由于其隐蔽性,增加了疫情防控难度,严格筛查和管理可疑暴露人员,及早发现无症状感染者,对防止疫情社区传播的意义重大。[Objective]To analyze a family clustering of coronavirus disease 2019(COVID-19)associated with the exposure to an asymptomatic case,and to provide evidences of developing strategies for COVID-19 prevention.[Methods]Epidemiological investigation was conducted on a COVID-19 family cluster(1 confirmed case and 2 asymptomatic cases).The specimens of the cases were tested for 2019 novel coronavirus nucleic acid with real-time fluorescence quantitative polymerase chain reaction.[Results]The clustering epidemic occurred in a family.Two asymptomatic cases B and C(B’s son)had Wuhan residential history.After arrival in Beijing on January 24,2020,B stayed in his mother's house.One family member A(B’s mother)developed the disease on February 7,2020,while the other two family members D and E(B’s wife and brother)did not develop the disease,and they were managed as close contacts.[Conclusion]This family COVID-19 clustering is induced by the exposure to an asymptomatic case.Identification of asymptomatic cases is very important for the control of COVID-19 epidemic.

关 键 词：新型冠状病毒肺炎 新型冠状病毒 无症状感染 家庭聚集性 流行病学分析 

分 类 号：R183.3[医药卫生—流行病学]