1,3,2-氧氮磷杂环戊烷衍生物(Ⅱ)——2-二乙氨基-3-取代甲酰基-1,3,2-氧氮磷杂环戊烷衍生物的合成及其性质研究  

1, 3,2-Oxazaphospholidine Derivatives(Ⅱ)——Studies on Synthesis and Properties of 2-Diethylamino 3-Substituted Formyl-1,3,2-Oxazaphospholidines

作　　者：杨华铮[1] 邵久书[1,2] 王惠林 陈茹玉[1] Yang Huazheng;Shao Jiushu;Wang Huilin;Chen Ruyu(Institute of Elemento-Organic Chemistry,Nankai University,Tianjin)

机构地区：[1]南开大学元素有机化学研究所 [2]天津市计划生育研究所

出　　处：《高等学校化学学报》1988年第10期1016-1022,共7页Chemical Journal of Chinese Universities

基　　金：中国科学院自然科学基金。

摘　　要：用六乙基亚磷酰胺与N-(β-羟基乙基)取代甲酰胺进行成环反应,合成了一系列新的有机磷杂环化合物,2-二乙氨基-3-取代甲酰基-1,3,2-氧氮磷杂环戊烷,然后与硫作用生成2-硫逐代衍生物,亦可不经分离一步完成上述反应。A series of new 2-diethylamino 3-substituted formyl-1,3,2-oxazaphospho-lidine derivatives (Ⅰ) have been prepared by the reaction of tris (diethylamino) phosphine with N-(β-hydroxyethyl) substituted amides. When (Ⅰ) was refluxed with sulfur in benzene, its 2-thione derivative (Ⅱ) was obtained. Compound(Ⅱ) can also be synthesized directly in one pot without the separation and purification of intermediate (Ⅰ). The IR, 1HNMR and MS spectra of these compounds have been discussed.

关 键 词：杂环化合物 氧氮磷杂环戊烷 

分 类 号：O62[理学—有机化学]