乳腺原发性粒细胞肉瘤临床病理学特征及生物学行为  

Granulocytic sarcoma of breast:clinical histopathologic and biological behavior

作　　者：刘新丽 梁锐 Liu Xinli;Liang Rui(Department of Pathology,the Second Hospital of Tianjin Medical University,Tianjin 300211,China)

机构地区：[1]天津医科大学第二医院病理科,300211

出　　处：《中华内分泌外科杂志》2021年第5期554-556,共3页Chinese Journal of Endocrine Surgery

基　　金：天津医科大学第二医院青年科研基金项目-自然科学孵育基金(2020ydey20)。

摘　　要：乳腺原发性粒细胞肉瘤(granulocytic sarcoma,GS)罕见,组织学形态和免疫表型类似粒细胞白血病,影像学缺乏特异性,类似于乳腺癌或乳腺脓肿。对其认识的重要性在于不能误诊为浸润性癌,特别是在冰冻诊断时误诊而导致过度手术。本研究收集3例乳腺粒细胞肉瘤病例,标本均充分取材,完善临床及预后资料,观察临床病理学特点,SP法免疫组织化学检测。探讨乳腺粒细胞肉瘤临床病理学特征,免疫组织化学特点,诊断及预后,以提高对本病的认识。granulocytic sarcoma(GS)is rare in the breast,histologically and immunophenotypically similar to myelogenous leukemia,radiologically lacking specificity,similar to breast cancer or mammary abscess.It should not be misdiagnosed as invasive cancer,especially in the case of frozen diagnosis,leading to excessive surgery.Three cases of GS were collected,specimens were fully drawn,microscopic pathologic examinations and immunohistochemistry(SP method)granulocytic sarcoma of breast were performed.The clinicopathological,immunohistochemical features,diagnosis and prognosis of GS are discussed to improve the awareness of the disease.

关 键 词：乳腺肿瘤 髓系肉瘤 粒细胞肉瘤 免疫组织化学 血象及骨髓象检查 

分 类 号：R655.8[医药卫生—外科学] R737.9[医药卫生—临床医学]