维生素A缺乏致小儿贫血的机制研究进展  

Research progress in the mechanism of vitamin A deficiency causing anemia in children

作　　者：王海伟 穆亚平[1] 李玢[1] WANG Haiwei;MU Yaping;LI Bin(Shenyang Children's Hospital,Shenyang 110000,China)

机构地区：[1]沈阳市儿童医院小儿血液科,沈阳110000

出　　处：《中国中西医结合儿科学》2021年第5期381-383,共3页Chinese Pediatrics of Integrated Traditional and Western Medicine

摘　　要：维生素A是人类机体必不可少的脂溶性维生素,特别是在儿童、妊娠及哺乳期妇女中。儿童时期缺乏维生素A可导致干眼症,降低机体抵抗力,增加机体感染的风险。维生素A缺乏导致儿童贫血的机制包括:限制造血基因表达、红细胞膜的稳定性遭到破坏、减少促红细胞生成素水平进而抑制造血、影响机体铁代谢,减少造血原材料的提供等,本文就维生素A缺乏导致儿童贫血的发病机制做一简要综述。Vitamin A is an essential fat-soluble vitamin in human body,especially to children,pregnant and lactating women.Vitamin A deficiency in childhood is known to cause dry eyes,lower body resistance and increase the risk of infection.The pathogenesis of anemia in children caused by vitamin A deficiency includes restriction of hematopoietic gene expression,destruction of erythrocyte membrane stability,reduction of EPO level and hematopoietic inhibition,influence on iron metabolism,and reduction of hematopoietic raw materials,etc.This paper summarizes the pathogenesis of anemia caused by vitamin A deficiency in children.

关 键 词：维生素A 贫血 维生素A缺乏 公共卫生 

分 类 号：R556[医药卫生—血液循环系统疾病]