肠三针治疗脓毒症肠功能障碍的临床疗效观察  

Clinical efficacy of electroacupuncture at"Intestine Three Needles"in the treatment of intestinal dysfunction in sepsis

作　　者：孙芳园[1] 卢明 沈伟鸿 SUN Fang-yuan;LU Ming;SHEN Wei-hong(Department of Intensive Care Medicine,The Seventh People′s Hospital of Shanghai University of TCM,Shanghai 200137,China;Trauma Emergency Center,The Seventh People′s Hospital of Shanghai University of TCM,Shanghai 200137,China)

机构地区：[1]上海中医药大学附属第七人民医院重症医学科,上海200137 [2]上海中医药大学附属第七人民医院急救创伤中心,上海200137

出　　处：《蚌埠医学院学报》2021年第10期1357-1359,1364,共4页Journal of Bengbu Medical College

基　　金：国家自然科学基金面上项目(81973649);上海市健委卫生行业临床研究专项(20214Y0281);浦东新区卫生系统浦东名中医继承人培养计划(PWRzj2020-02);上海市浦东新区科技发展基金民生科研专项(PKJ2019-Y16);上海中医药大学附属第七人民医院人才培养计划(XX2019-20)。

摘　　要：目的:探讨电针肠三针对脓毒症肠功能障碍的改善效果。方法:将60例脓毒症肠功能障碍病人,随机分为观察组和对照组,各30例,观察治疗前及治疗后7 d的临床疗效、血清炎症指标、血浆胃动素水平、胃肠功能指标、APACHE-Ⅱ评分、胃肠功能AGI评分情况。结果:2组病人治疗前各指标差异均无统计学意义(P>0.05),治疗后血清炎症指标、排便测量分、腹围、腹内压、APACHE-Ⅱ评分、胃肠功能AGI评分均下降,血浆胃动素水平、每分钟肠鸣音次数均升高,且观察组均优于对照组,差异均有统计学意义(P<0.05~P<0.01);治疗7 d后观察组总有效率优于对照组(P<0.05)。结论:电针肠三针能显著增强脓毒症病人胃肠动力,减弱胃肠道炎症反应,改善胃肠道功能。Objective:To observe the clinical efficacy of electroacupuncture at"Intestine Three Needles"in the treatment of intestinal dysfunction in sepsis.Methods:A total of 60 sepsis patients with intestinal dysfunction were randomly divided into the control group and observation group(30 cases in each group).The clinical efficacy,serum inflammatory markers,plasma motilin level,gastrointestinal function index,APACHE-Ⅱscore and gastrointestinal function AGI score in two groups were observed before and after 7 days of treatment.Results:There was no statistical significance in each index between two groups before treatment(P>0.05).After treatment,the serum inflammation index,measuring points of defecating,intra-abdominal pressure,abdomen circumference,APACHE-Ⅱscore and gastrointestinal AGI score decreased,the motilin level and number of bowel sounds per minute increased,and the above indexes in observation group were better than those in control group(P<0.05 to P<0.01).The total effective rate in observation group was better than that in control group after 7 days of treatment(P<0.05).Conclusions:Electroacupuncture at“Intestine Three Needles”can significantly enhance the gastrointestinal motility,reduce the gastrointestinal inflammation and improve the gastrointestinal function.

关 键 词：脓毒症 肠功能障碍 肠三针 

分 类 号：R459.7[医药卫生—急诊医学] R245[医药卫生—治疗学]