多取代吡咯的合成及其性质(Ⅱ)  

Synthesis and Propertion of Polysubstitution Pyrrole

作　　者：李葆[1] 张书文[1] Li Bao;Zhang Shuwpn(Department of Clemistry,Jilin Teacher's College,Jilin)

机构地区：[1]吉林师范学院化学系

出　　处：《高等学校化学学报》1985年第6期513-514,共2页Chemical Journal of Chinese Universities

摘　　要：前文已报导1-芳基-2-甲基-3-乙酰基-5-对氯苯基吡咯^([1])。本文用间硝基-ω-溴代苯乙酮^([2])与乙酰丙酮作用,得到1-间硝基苯基-3-乙酰基-1,4-戊二酮(1)^([3]),(1)与各种不同的芳香族伯胺在冰醋酸存在下进行环合反应,生成1,2,3,5-四取代吡咯(2)至(10)^([4])。后者与氨基脲反应得到相应的缩氨脲^([5,6])。这些都是新化合物,其性质见下。Acetylacetones were treated by m-nitro-ω-bromoacetophenones to give l-(m-nitrophenyl) -3-acetyl-1, 4-pentandiketone( 1 ). 9 new 1-aryl-2-methyl-3-acetyl-5-(m-nitrophenyl)pyrroles (2)-( 10) have been synthesized by reaction of (1)with various primary amines. Semicarbazoncs were prepared from (2)-(10).Compounds(1)-(10) and the Semicarbazoncs were reported for the first time.

关 键 词：戊二酮 缩氨脲 氨基脲 (Ⅱ) 环合反应 乙酰丙酮 芳香族伯胺 芳基 

分 类 号：O62[理学—有机化学]