基于苯并呋咱胺类衍生物的碱性荧光探针  

The PH Fluorescent Probe Based on Benzofuroxan Amine Derivatives

作　　者：张中岩 刘诗莹 许金松 卢娉婷 刘欣[1] 李煦田 马立军[1] ZHANG Zhongyan;LIU Shiying;XU Jinsong;LU Pinting;LIU Xin;LI Xutian;MA Lijun(School of Chemistry, South China Normal University, Guangzhou 510006, China)

机构地区：[1]华南师范大学化学学院,广州510006

出　　处：《华南师范大学学报（自然科学版）》2021年第5期17-22,共6页Journal of South China Normal University(Natural Science Edition)

基　　金：广东省自然科学基金项目(2015A030313392);广州市科技计划项目(2018J2200342)。

摘　　要：以4-氯-7-硝基苯并呋咱(NBD-Cl)为原料,设计、合成了3种荧光化合物(NBD-N、NBD-NH、NBD-NH2),通过质谱、核磁共振对其结构进行了表征.研究表明:这3种化合物在pH 7.0~12.0范围内对水溶液的酸碱度具有可逆的荧光识别响应.同时,其他常见离子的共存并不影响3种化合物对pH的荧光识别.因此,这3种化合物可作为碱性pH荧光探针.The fluorescent probes(NBD-N,NBD-NH,NBD-NH2)were designed and synthesized using 4-chloro-7-nitrobenzofurazan(NBD-Cl).The structure of the probes was characterized with mass spectrometry and nuclear magnetism.It can recognize the pH of the aqueous solution in a reversible response within the pH range of 7.0~12.0.In addition,the coexistence of other common ions does not affect the fluorescent recognition signals of the three compounds.Therefore,the three compounds can be used for alkaline pH fluorescent probes.

关 键 词：PH 荧光探针 苯并呋咱 NBD-Cl 

分 类 号：O657.3[理学—分析化学]