血清白蛋白水平与老年冠心病患者PCI术后心源性死亡的关系研究  

Study of the correlation between serum albumin levels and cardiac death after PCI in elderly patients with coronary artery disease

作　　者：赵翔宇 王逸 殷安康 孙学英 唐乙月 焦云根[1] ZHAO Xiang-yu;WANG Yi;YIN An-kang(Department of Cardiology,Affiliated Hospital of Yangzhou University,Yangzhou 225000,China)

机构地区：[1]扬州大学附属医院心血管内科,225000

出　　处：《中国实用医药》2021年第30期4-6,共3页China Practical Medicine

摘　　要：目的探究血清白蛋白水平与老年冠心病患者经皮冠状动脉介入治疗(PCI)术后心源性死亡之间的关系。方法回顾性分析500例老年冠心病患者的临床资料,所有患者均行PCI,于术后对患者进行随访,对患者一般资料行单因素分析,再经多因素Logistic回归分析老年冠心病患者PCI术后心源性死亡的影响因素,分析血清白蛋白水平与PCI术后心源性死亡之间的关系。结果研究中500例患者PCI术后均持续接受随访,中位随访时间为12.5个月,未出现失访患者。随访期间,共有35例患者心源性死亡,死亡率为7.00%,将其归为心源性死亡组,存活的465例患者归为存活组,存活率为93.00%。心源性死亡组与存活组患者性别、饮酒史、高血压史、糖尿病史、低密度脂蛋白胆固醇(LDL-C)、总胆固醇(TC)、甘油三酯(TG)比较,差异无统计学意义(P>0.05);心源性死亡组与存活组患者年龄、吸烟史、心率、高密度脂蛋白胆固醇(HDL-C)、白蛋白水平比较,差异有统计学意义(P<0.05)。多因素Logistic回归模型显示,影响老年冠心病患者PCI术后心源性死亡的危险因素包括年龄、吸烟史、白蛋白水平(P<0.05)。结论血清白蛋白水平是影响老年冠心病患者PCI术后心源性死亡的一个重要危险因素,早期纠正血清白蛋白水平利于改善预后。Objective To investigate the correlation between serum albumin levels and cardiac death after percutaneous coronary intervention(PCI)in elderly patients with coronary artery disease.Methods The clinical data of 500 elderly patients with coronary heart disease were retrospectively analyzed,and all patients underwent PCI.All patients were followed up after PCI,and the general data of patients were analyzed by univariate analysis,and then the factors influencing cardiac death after PCI in elderly patients with coronary artery disease were analyzed by multivariate Logistic regression analysis.The correlation between serum albumin level and cardiac death after PCI was analyzed.Results All 500 patients in the study received continuous follow-up after PCI,with a median follow-up time of 12.5 months,and there were no patients lost to follow-up.During the follow-up period,35 patients were cardiac death,with a mortality rate of 7.00%,which was classified as the cardiac death group,and 465 patients who survived were classified as the survival group,with a survival rate of 93.00%.There was no statistically significant difference between the cardiac death group and the survival group in terms of gender,history of drinking,history of hypertension,history of diabetes mellitus,low-density lipoprotein cholesterol(LDL-C),total cholesterol(TC),triglyceride(TG)(P>0.05).The differences in age,smoking history,heart rate,high-density lipoprotein cholesterol(HDL-C),and albumin levels between the cardiac death group and the survival group were statistically significant(P<0.05).The multivariate Logistic regression model showed that the risk factors of cardiac death in elderly patients with coronary heart disease after PCI included age,smoking history,and albumin level(P<0.05).Conclusion Serum albumin level is an important risk factor for cardiac death after PCI in elderly patients with coronary heart disease,and early correction of serum albumin level is beneficial to improve the prognosis.

关 键 词：血清白蛋白水平 老年冠心病 经皮冠状动脉介入术 心源性死亡 危险因素 

分 类 号：R541.4[医药卫生—心血管疾病]