罗哌卡因与布比卡因用于腰-硬联合麻醉的临床疗效对比  

Comparative Clinical Effect of Ropivacaine and Bupivacaine in Combined Sspinal and Epidural Anesthesia

作　　者：翟春丽 ZHAI Chunli(Huludao Second People's Hospital,Huludao 125001,China)

机构地区：[1]葫芦岛市第二人民医院,辽宁葫芦岛125001

出　　处：《中国医药指南》2021年第29期37-39,共3页Guide of China Medicine

摘　　要：目的本次试验将采用罗哌卡因与布比卡因对腰-硬联合麻醉的临床效果进行分析,更好地为手术提供服务。方法本次试验选取了2018年6月至2019年5月前来本院进行疾病检查及治疗的患者为对象,经过专业科室检查,开展下腹手术治疗。在自愿参与试验调查的患者中,采用计算机随机数字表法,对120例患者进行麻醉使用效果的讨论。对照组患者采用布比卡因,观察组则为罗哌卡因,分析不同麻醉方式所产生的临床效果和使用安全性。结果观察组为腰硬联合麻醉的起效时间为(3.82±2.51)min,对照组为(3.52±1.86)min,与此同时,观察组在T10节段镇痛时间上为(146.24±1.74)min,对照组则为(114.58±1.63)min,组间对比差异较为显著,具有统计学意义(P<0.05)。在运动阻滞的持续时间上,观察组为(271.36±1.52)min,短于对照组的(224.36±1.29)min,组间对比差异较为显著(P<0.05)。在感觉阻滞起效时间上,观察组为(73.60±7.60)s,对照组为(62.30±3.90)s,在感觉阻滞持续时间上观察组为(223.24±1.52)s,对照组为(158.63±1.89)s,组间对比差异显著(P<0.05)。同时,改良Bromage评估法的总评分上,观察组为(1.65±0.54)分,对照组为(1.95±0.57)分,组间对比差异显著(P<0.05)。观察组患者的不良反应发生率为5.00%(3/60),明显低于对照组的11.67%(7/60),差异具有统计学意义(P<0.05)。在HR、SpO_(2)、MAP的指标上,麻醉前和首次注入麻醉药后,两组对比无差异(P>0.05);但是在给药后5 min和10 min则有明显差异(P<0.05)。结论采用罗哌卡因在腰硬联合麻醉上更为安全、起效速度快,能够为手术治疗提供便捷和保障,有利于患者手术后的早日恢复,是有效地局部麻醉用药,可以推广应用。Objective This experiment will use ropivacaine and bupivacaine to analyze the clinical effect of combined spinal and epidural anesthesia,so as to provide better service for surgery.Methods From June 2018 to may 2019,the patients who came to our hospital for disease examination and treatment were selected as the subjects in this experiment.After professional department examination,they carried out lower abdominal surgery.Among the patients who voluntarily participated in the experimental investigation,120 patients were used to discuss the effect of anesthesia by using the method of computer random number table.Bupivacaine was used in the control group and ropivacaine was used in the observation group.Results The onset time of combined spinal-epidural anesthesia in the observation group was(3.82±2.51)min,and the control group was(3.52±1.86)min.At the same time,the time of T10 analgesia in the observation group was(146.24±1.74)min.The control group is(114.58±1.63)min,the difference between the groups is more significant,with statistical significance(P<0.05).In the duration of exercise block,the observation group was(271.36±1.52)min,which was shorter than the control group(224.36±1.29)min,and the difference between the groups was significant(P<0.05).On the onset time of sensory block,the observation group was(73.60±7.60)s,the control group was(62.30±3.90)s,the duration of sensory block was(223.24±1.52)s in the observation group,and the control group was(158.63±1.89)s,the difference between the groups was significant(P<0.05).At the same time,the total score of the modified Bromage assessment method was(1.65±0.54)points for the observation group and(1.95±0.57)points for the control group,and the difference between the groups was significant(P<0.05).The incidence of adverse reactions in the observation group was 5.00%(3/60),which was significantly lower than the 11.67%(7/60)in the control group,and the difference was statistically significant(P<0.05).In the indicators of HR,SpO_(2) and MAP,there was no diffe

关 键 词：罗哌卡因 布比卡因 腰-硬联合麻醉 不良反应 

分 类 号：R614[医药卫生—麻醉学]