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作 者:尤俊霞 钟细妹 黄平[1] YOU Junxia;ZHONG Ximei;HUANG Ping(Songgang People's Hospital of Baoan District, Shenzhen, Guangdong Province, 518105)
出 处:《中国计划生育学杂志》2021年第8期1582-1586,共5页Chinese Journal of Family Planning
摘 要:目的:分析宫腔镜系统(HEOS)治疗宫腔粘连效果及影响因素。方法:本院2018年1月-2020年1月收治的106例符合纳入标准的宫腔粘连患者随机分为观察组和对照组各53例,对照组采用常规宫腔镜手术方案治疗,观察组采用HEOS治疗。统计术中出血量、手术时间、术中并发症情况;手术前及治疗3个月时检测血清中孕酮(P)和雌二醇(E2)水平,B超测量子宫内膜厚度;术后3个月记录患者临床疗效;采用logistics回归模型分析影响HEOS治疗效果的影响因素。结果:观察组手术时间(13.2±3.5min)低于对照组(22.4±4.6 min),治疗后观察组临床疗效(92.5%)、血清P(40.86±4.12 nmol/L)和E2(487.98±12.05 nmol/L)水平及子宫内膜厚度(8.87±0.83mm)均高于对照组(83.0%、37.25±5.58 nmol/L、476.15±13.58 nmol/L、6.48±0.92mm)(均P<0.05);宫腔粘连患者病程长、宫腔粘连范围大、粘连性质致密、放置宫内节育器及粘连分级重均为影响HEOS术后效果的独立危险因素(P<0.05)。结论:HEOS治疗宫腔粘连可显著提高临床疗效,同时提示临床对患者可能存在的治疗影响因素术前应加以重视,以提高治疗效果。Objective:To analyze the effect of HEOS hysteroscopy for treating patients with intrauterine adhesions,and to study the influence factor of the curative effect.Methods:A total of 106 patients with intrauterine adhesions were included and were randomly divided into observation group and control group from January 2018 to January 2020.The patients in the control group were treated with conventional hysteroscopic surgery,and the patients in the observation group were treated with HEOS Laparoscopic surgery.The intraoperative blood loss,operation time,intraoperative complications of the patients in the two groups were analyzed.The serum progesterone(P)and estradiol(E2)levels before operation and 3 months after operation of the patients in the two groups were detected.B-ultrasound was used to measurementthe endometrial thickness of the patients.The clinical efficacy of the patient in the two groups 3 months after the operation was recorded.Logistic regression model was used to analyze the factors affecting the clinical efficacy of HEOS hysteroscopy.Results:The operation time(13.2±3.5min)of the patient in the observation group was significant lower than that(22.4±4.6 min)of the patient in the control group.After treatment,the clinical efficacy(92.5%),the serum P level(40.86±4.12 nmol/L),the serum E2 level(487.98±12.05 nmol/L),and the endometrial thickness(8.87±0.83mm)of the patient in the observation group were significant higher than those(83.0%,37.25±5.58 Nmol/L,476.15±13.58 nmol/L,and 6.48±0.92mm)of the patient in the control group(all P<0.05).As for the patients with intrauterine adhesions,the long course of disease,wide range of intrauterine adhesions,dense nature of adhesions,placement of intrauterine device and,high grade of adhesions were the independent risk factors affecting the postoperative effect of HEOS hysteroscopy(P<0.05).Conclusion:HEOS hysteroscopy for treating the patient with intrauterine adhesions can significantly improve the clinical efficacy.It is suggested that preoperative attention sho
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