机构地区:[1]青海省妇幼保健院,西宁810000
出 处:《中国计划生育学杂志》2021年第8期1660-1663,1668,共5页Chinese Journal of Family Planning
摘 要:目的:探究口服中药汤剂及穴位贴敷对输卵管通液术治疗输卵管性不孕症临床效果,并分析对患者血清炎症因子影响。方法:选取2017年1月-2019年1月本院妇科收治的输卵管性不孕症患者240例,随机分为3组各80例,分别采用常规输卵管通液术(通液组)、口服中药汤剂联合输卵管通液术(口服组)、口服中药汤剂+穴位贴敷联合输卵管通液术治疗(联合组)。HSG检查各组输卵管通畅情况,检测并分析治疗前后3组血清子宫内膜细胞黏附分子-1(ICAM-1)、白细胞介素-6(IL-6)水平及妊娠状况。结果:治疗后输卵管通畅率联合组(64.3%)高于口服组(54.8%)、通液组(44.6%)(P<0.05)。ICAM-1、IL-6水平3组均低于治疗前,且联合组低于另外两组(P<0.05)。治疗总有效率联合组(83.8%)高于口服组(72.5%)和通液组(61.3%)(P<0.05)。治疗期间,口服组和联合组均有个别患者出现腹泻,通过辩证调整汤剂药方后患者腹泻症状消失。治疗后随访12个月内,宫内妊娠率联合组(58.8%)高于口服组(48.8%)和通液组(37.5%)(P<0.05)。结论:中药汤剂联合穴位贴敷能够有效提高输卵管通液术治疗输卵管性不孕症效果,可降低患者血清炎症因子表达。Objective:To explore the clinical effect of oral decoction of traditional Chinese medicine combined with acupoint application for assisted treating women with tubal infertility,and to analyze its influence on serum inflammatory factors.Methods:240 women with tubal infertility were randomly divided into group A,group B and group C(80 cases in each group)from January 2017 to January 2019.The women in group A were treated by conventional tubal hydrotherapy,the women in group B were treated by oral dialectical decoction of traditional Chinese medicine combined with hydrotubation,and the women in group C treated by hydrotubation combined with oral dialectical decoction of traditional Chinese medicine traditional Chinese medicine and acupoint.The tubal patency of the women in the three groups was examined by hystero-salpingography(HSG).The serum endometrial intercellular adhesion molecule-1(ICAM-1)and interleukin-6(IL-6)levels,and pregnancy status of the women in the three groups were detected and analyzed before and after treatment.Results:After treatment,the tubal patency rate(64.3%)of the women in group C was significant higher than that(54.8%)of the women in group B and that(44.6%)of the women in group A(P<0.05).The levels of ICAM-1 and IL-6 of the women in the three groups were significant lower than those of the women in the three groups before treatment,and those of the women in group C were significant lower than those of the women in the other two groups(P<0.05).The total effective rate(83.8%)of the women in group C was significant higher than that(72.5%)of the women in group B and that(61.3%)of the women in group A(P<0.05).During the treatment,some women in Group B and Group C had diarrhea,and the diarrhea symptoms of them disappeared after dialectical adjustment of the decoction prescription.The rate of intrauterine pregnancy(58.8%)of the women in group C within 12 months after treatment was significant higher than that(48.8%)of the women in group B and that(37.5%)of the women in group A(P<0.05).Conclusion:O
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