子宫动脉栓塞术治疗前置胎盘剖宫产产后出血对患者应激反应及性激素的影响  

Influce of uterine artery embolization for treating postpartum hemorrhage after cesarean section in women with placenta previa on their stress response and ovarian reserve

作　　者：靳健美 肖琳[1] 胡又丹[1] JIN Jianmei;XIAO Lin;HU Youdan(Dazhou Integrated TCM & Western Medicine Hospital,Dazhou, Sichuan Province, 635000)

机构地区：[1]四川省达州市中西医结合医院,635000

出　　处：《中国计划生育学杂志》2021年第8期1741-1744,1748,共5页Chinese Journal of Family Planning

摘　　要：目的:探究子宫动脉栓塞术治疗前置胎盘剖宫产产后出血对患者应激反应及卵巢储备功能的影响。方法:回顾性收集2019年1月-2020年3月本院因前置胎盘剖宫产产后出血患者84例临床资料,根据治疗方法不同分为B-Lynch缝合法治疗的缝合法组40例,子宫动脉栓塞术治疗的动脉栓塞组44例。观察两种方法止血效果,比较两组产前及术后血清应激反应指标丙二醛(MDA)、超氧化物歧化酶(SOD)、过氧化氢酶(CAT),产前和术后3、6个月卵巢储备功能指标血清雌二醇(E2)、卵泡刺激素(FSH)、黄体生成激素(LH)。结果:动脉栓塞组止血有效率(95.4%)与缝合法组(92.5%)无差异(P>0.05)。两组术后血清MDA均低于产前,SOD、CAT水平均高于产前,术后3、6个月FSH、LH水平均高于产前,E2水平均低于产前,术后6个月FSH、LH、E2水平均低于术后3个月(P<0.05)。动脉栓塞组术后MDA水平低于缝合法组,SOD、CAT水平均高于缝合法组,术后3、6个月FSH、LH、E水平均高于缝合法组(均P<0.05)。结论:子宫动脉栓塞术治疗前置胎盘剖宫产产后出血效果确切,且可有效减轻患者应激反应,降低对患者术后卵巢储备功能的影响,助于患者恢复。Objective:To explore the effect of uterine artery embolization for treating postpartum hemorrhage of women with placenta previa after cesarean section on their stress response and ovarian reserve.Methods:The clinical data of 84 women with placenta previa and postpartum hemorrhage after cesarean section from January 2019 to March 2020 were collected retrospectively.According to the different treatment methods,these women were divided into group A(44 women given uterine artery embolization)and group B(40 women given B-lynch suture).The hemostatic efficiency of the women in the two groups was observed.The stress response indexes,such as the levels of serum malondialdehyde(MDA),superoxide dismutase(SOD),and catalase(CAT)before and after cesarean section,and the ovarian reserve indexes,such as the levels of serum estradiol(E2),follicle stimulating hormone(FSH),and luteinizing hormone(LH)before and in 3 and 6 months after cesarean section were compared between the two groups.Results:There was no significant difference in hemostasis rate(95.4%vs.92.5%)of the women between the two groups(P>0.05).The levels of serum MDA of the women in the two groups had decreased significantly after cesarean section,but SOD and CAT had increased significantly.The levels of FSH and LH of the women in the two groups had increased significantly in 3 and 6 months after cesarean section,but the E2 level had decreased significantly.The levels of FSH,LH,and E2 of the women in the two groups in 6 months after cesarean section were significant lower than those in 3 months(P<0.05)。The postoperative MDA level of the women in group A was significant lower than that of the women in group B,but the levels of postoperative SOD and CAT of the women in group A were significant higher,and the levels of FSH,LH and E of the women in group A in 3 and 6 months after cesarean section were significant higher than those in group B(all P<0.05).Conclusion:Uterine artery embolization for treating the women with placenta previa and postpartum hemorrhage after cesa

关 键 词：前置胎盘 剖宫产产后出血 子宫动脉栓塞术 应激反应 性激素功能 

分 类 号：R714.461[医药卫生—妇产科学]