运动康复训练对射血分数保留的心力衰竭患者预后改善的研究  

Study on the effect of exercise rehabilitation training on prognosis improvement of patients with heart failure with preserved ejection fraction

作　　者：周冰洁 李玉梅 罗向卫 谢宗明 ZHOU Bingjie;LI Yumei;LUO Xiangwei;XIE Zongming(The Second Department of Cardiovascular Medicine,Yangchun People's Hospital,Guangdong,Yangchun 529600,China)

机构地区：[1]广东省阳春市人民医院心血管内科二区,广东阳春529600

出　　处：《中国医药科学》2021年第20期182-185,193,共5页China Medicine And Pharmacy

基　　金：广东省阳江市科技计划项目[阳科通(2019)50号-105]。

摘　　要：目的探析运动康复训练对慢性射血分数保留心力衰竭(HFpEF)患者预后的改善效果。方法选取2019年8月至2020年8月阳春市人民医院收治的慢性HFpEF患者150例作为研究对象,以随机对照原则将其分为运动康复训练组和对照组,每组各75例,两组患者均接受慢性心力衰竭标准化药物治疗,运动康复训练组在药物治疗基础上予以运动康复训练,统计并比较两组患者运动代谢当量(MET)、6 min步行试验距离(6MWD)、2H2FPEF评分、舒张功能以及不良事件发生情况等指标间的差异。结果经不同方式干预后,运动康复训练组的静息心率、6MWD及MET均优于对照组,2H2FPEF评分低于对照组,且运动康复训练组患者训练后的心脏各项指标均优于对照组,差异有统计学意义(P<0.05);运动康复训练组的不良事件总发生率(6.67%)低于对照组(16.00%),差异有统计学意义(P<0.05)。结论运动康复训练有利于提升HFpEF患者的运动耐力,可有效改善患者心脏舒张功能及2H2FPEF评分,同时运动康复训练还可有效降低患者不良事件的发生风险。Objective To explore the effect of exercise rehabilitation training on the prognosis improvement of patients with heart failure with preserved ejection fraction(HFpEF).Methods A total of 150 patients with HFpEF in Yangchun People's Hospital from August 2019 to August 2020 were selected as the research objects,and were randomly divided into training group and control group,with 75 cases in each group.Both patients received standardized drug treatment for chronic heart failure,and the training group was given exercise rehabilitation training on this basis.The metabolic equivalent(MET),6-minute walk distance(6MWD),2H2FPEF score,diastolic function and adverse events were recorded and compared between the two groups.Results After different interventions,the resting heart rate,blood pressure,6MWD and MET of the training group were bett er than t hose of the c ontrol group,and the 2H2FPEF score af ter training was lower tha n that of the control group.All cardiac indexes of the training group after training were better than that in the control group,with statistically significant differences(P<0.05).The total incidence of adverse events(6.67%)was lower than that of the control group(16.00%),all with statistically significant difference(P<0.05).Conclusion Exercise rehabilitation training is beneficial to improve the exercise endurance of patients with HFPEF,and can effectively improve their diastolic function and 2H2FPEF score.Meanwhile,exercise rehabilitation training can also effectively reduce the risk of adverse events.

关 键 词：慢性射血分数保留 心力衰竭 运动康复 预后 

分 类 号：R541.6[医药卫生—心血管疾病]