吡啶-2-羧酸铬的制备研究  

Study on the Preparation of Chromium Pyridine-2-carboxylate

作　　者：薛建锋 朱小刚 刘芳 卢乐 徐笑天 俞新南 Xue Jianfeng;Zhu Xiaogang;Liu Fang;Lu Le;Xu Xiaotian;Yu Xinnan(Nantong Acetate Chemical Co.,Ltd.,Nantong City,Nantong 226017,China)

机构地区：[1]南通醋酸化工股份有限公司,江苏南通226017

出　　处：《云南化工》2021年第10期55-58,共4页Yunnan Chemical Technology

摘　　要：采用2-氰基吡啶为主要原料,经过水解,直接络合得到吡啶-2-羧酸铬。确定了络合反应的物质的量比,n (吡啶-2-羧酸)∶n (三氯化铬)=1.01∶1,回流反应,络合pH在5~7。产品质量分数达到99.7%(HPLC)以上。以2-氰基吡啶计,吡啶-2-羧酸铬收率99%。该工艺不需提取吡啶-2-羧酸中间体,反应液直接络合,缩短了制备流程,工艺条件稳定可控,产品质量达到国内先进水平。Pyridine-2-carboxylate chromium is directly synthesized by the hydrolysis of 2-cyanopyridine. The product content reaches99. 7%( HPLC) above when the molar ratio of pyridine-2-carboxylic acid to chromium trichloride is 1. 01: 1 and p H is 5 ~ 7 at reflux reaction. As measured by 2-cyanopyridine,the yield of pyridine-2-carboxylate chromium is 99%. The process does not need to extract the intermediate of pyridine-2-carboxylic acid through the reaction solution is directly complexed. The preparation process is shortened,and the process condition are stable and controllable. Importantly the product quality reaches the domestic advanced level.

关 键 词：吡啶-2-羧酸铬 络合 水解 2-氰基吡啶 

分 类 号：TQ351.36[化学工程]