新生儿溶血病(HDN)患儿的实验室检测结果及相关影响因素分析  

Laboratory test results and related influencing factors of children with hemolytic disease of the newborn(HDN)

作　　者：孙佳慧 SUN Jia-hui(Suzhou First People's Hospital,Suzhou 234000,Anhui)

机构地区：[1]宿州市第一人民医院,安徽宿州234000

出　　处：《安徽医专学报》2021年第5期83-85,共3页Journal of Anhui Medical College

摘　　要：目的:探讨新生儿溶血病(HDN)患儿的实验室检测结果及相关影响因素。方法:通过选取某医院304例疑似HDN患儿开展研究,其中包括132例ABO-HDN确诊患儿(确诊组),52例可疑患儿(可疑组),120例阴性患儿(对照组),分析三组实验室检验结果以及影响因素。结果:三组的CK、α-HBD、TBIL和LD指标差异均存在统计学意义(P<0.05);日龄和体质量的差异对于HDN阳性检出率差异有统计学意义(P<0.05);孕周、母亲怀孕次数、性别及血型的差异对于患儿的HDN阳性检出率均基本一致(P>0.05)。结论:HDN患儿的阳性检出率与新生儿日龄和体质量密切相关,与患儿性别、母亲怀孕次数、孕周和血型无关,为患儿展开早期溶血检查,能够获取到显著诊断结果,具有推广价值。Objective:To analyze the laboratory test results and related influencing factors of children with hemolytic disease of newborn(HDN).Methods:304 children with suspected HDN in hospital were selected for this study,including 132 patients diagnosed with ABO-HDN(diagnosis group),52 suspicious patients(suspicious group)and 120 negative patients(control group).Three groups of laboratory test results and influencing factors were analyzed.Results:CK indexes of the three groupsα-HBD There were significant differences in HBD index,TBIL index and LD index(P<0.05);The positive rate of HDN was statistically significant between days>4D,days≤4D,body weight≤3000 g and body weight>3000 g(P<0.05);The positive rates of HDN in children with gestational weeks<37 weeks and≥37 weeks,the number of pregnancies of mothers<1 and≥2,men and women,type a blood and type B blood were basically the same(P>0.05).Conclusion:the positive detection rate of children with HDN is closely related to neonatal age and weight,and has nothing to do with children's gender,current pregnancy times,gestational weeks and blood group.Early hemolysis test for children can obtain significant diagnostic results and has popularization value.

关 键 词：新生儿溶血病 实验室检测结果 影响因素 

分 类 号：R556.63[医药卫生—血液循环系统疾病]