新西兰兔骨缺损模型的文献综述  

A review on bone defect models in New Zealand rabbits

作　　者：艾子政 董谢平[1] AI Zi-zheng;DONG Xie-ping(Jiangxi Provincial Peopled Hospital,Nanchang University,Nanchang 330006,China;Postgraduate School,Jiangxi University of Traditional Chinese Medicine,Nanchang 330004,China)

机构地区：[1]江西省人民医院骨科,江西南昌330006 [2]江西中医药大学研究生院,江西南昌330004

出　　处：《中国矫形外科杂志》2021年第20期1863-1867,共5页Orthopedic Journal of China

基　　金：国家自然科学基金资助项目(编号:81860384)。

摘　　要：近年来,骨缺损动物模型在骨组织工程实验中运用广泛,新西兰兔是骨缺损修复实验中首选的实验动物之一,选用合适的骨缺损模型需考虑多种因素,如动物的年龄、性别、体重、日常活动量、骨缺损部位、缺损大小、骨膜血运情况、固定方式等,众多学者在制作模型时对上述因素有着不同的组合方式,但多未解释理由。为此,本文对以新西兰兔为实验动物的骨缺损模型进行综述。In recent years,bone defect animal model has been widely used in bone tissue engineering experiments.New Zealand rabbit is one of the first-choice experimental animals for creating bone defect in repairing experiment.It is necessary to consider various factors,such as age,sex,weight,daily activity,bone defect location,defect size,periosteal blood flow and fixation in the models.Many schol-ars have reported different combinations for the models based on the abovesaid factors,huwever,most of lliein had no explanation for the reasons.Therefore,this paper reviews the bone defect model making in New Zealand rabbits as experimental animals.

关 键 词：新西兰兔 骨缺损 动物模型 影响因素 综述 

分 类 号：R68[医药卫生—骨科学]