新的和严重药品不良反应126例分析研究  

Analysis and study of 126 new and serious adverse drug reactions

作　　者：陈倩倩 汪盛 李歆[3] 许岭[1] CHEN Qianqian;WANG Sheng;LI Xin;XU Ling(Department of Pharmacy,Nanjing Second Hospital,Nanjing,Jiangsu 210003,China;Department of Pharmacy,The First Affiliated Hospital of Wannan Medical College,Wuhu,Anhui 241001,China;School of Pharmacy,Nanjing Medical University,Nanjing,Jiangsu 211166,China)

机构地区：[1]南京市第二医院药学部,江苏南京210003 [2]皖南医学院第一附属医院药学部,安徽芜湖241001 [3]南京医科大学药学院,江苏南京211166

出　　处：《现代医药卫生》2021年第21期3600-3602,3606,共4页Journal of Modern Medicine & Health

基　　金：国家自然科学基金项目(71673147)。

摘　　要：目的研究新的和严重的药品不良反应(ADR)特点及其规律,为临床合理安全用药提供参考。方法收集南京市第二医院2020年1—12月上报的935例药品不良反应报告,对整理出126例新的和严重的ADR报告进行综合分析。结果126例新的和严重的ADR报告中,新的ADR有120例(占95.24%),严重的ADR有6例(占4.76%)。对症处理后,大部分ADR均痊愈或好转。口服致ADR病例数最多,其次为静脉滴注给药。结论应不断完善ADR监测,加强对新的和严重的ADR上报工作,提高新的和严重的ADR监测水平,减少ADR风险,进一步促进临床安全用药。Objective To study the characteristics and laws of new and serious ADRs to provide references for clinically reasonable and safe medication.Methods Collected 935 cases of adverse drug reaction reports from Nanjing Second Hospital from January to December 2020,and conducted a comprehensive analysis of 126 new and serious ADR reports.Results Among the 126 new and serious ADR reports,there were 120 new ADRs(95.24%)and 6 severe ADRs(4.76%).After symptomatic treatment,most ADRs were cured or improved.The number of ADR cases caused by oral administration was the largest,followed by intravenous drip.Conclusion ADR monitoring should be continuously improved,new and serious ADR reports should be strengthened,new and serious ADR monitoring levels should be improved,ADR risks should be reduced,and clinical safe drug use should be further promoted.

关 键 词：药品不良反应 严重 报告 监测 

分 类 号：R969.3[医药卫生—药理学]