间叔丁基苯乙醚高效液相色谱分析方法  

Analysis of 1-Tert-butyl-3-ethoxybenzene by HPLC

作　　者：汪雪娟 朱安琪 庞怀林 WANG Xue-juan;ZHU An-qi;PANG Huai-lin(CAC Shanghai Chemicals Co.,Ltd.,Shanghai 201612,China;CAC Nantong Chemicals Co.,Ltd.,Nantong 226407,China)

机构地区：[1]上海泰禾化工有限公司,上海201612 [2]南通泰禾化工股份有限公司,江苏南通226407

出　　处：《精细化工中间体》2021年第5期86-88,92,共4页Fine Chemical Intermediates

摘　　要：建立一种测定间叔丁基苯乙醚的高效液相色谱法。采用Eclipse XDB-C18不锈钢柱(250 mm×4.6 mm i.d.×5μm)和紫外检测器,以乙腈和水为流动相,流速为1.0 mL/min,在220 nm波长下对间叔丁基苯乙醚进行分离和定量分析。结果表明,该方法测得间叔丁基苯乙醚保留时间约12.5 min,线性相关系数为1.0000,标准偏差为0.02,变异系数为0.02%,平均回收率为100.02%。方法操作简便,精密度与准确度较高,可用于间叔丁基苯乙醚的定量分析。A HPLC method for the determination of 1-tert-butyl-3-ethoxybenzene was established.In this method,the sample was separated and analyzed under following conditions:Eclipse XDB-C18 stainless steel column(250 mm×4.6 mm i.d.×5μm)as the separation column;UV detertor at wavelength of 220 nm;acetonitrile and water as the mobile phase at a flow rate of 1.0 mL/min.Experimental results indicated that the retention time of 1-tert-butyl-3-ethoxybenzene was 12.5 min;the linear correlation coefficient was of 1.0000;the standard deviation was of 0.02;the variation coefficient was of 0.02%;and average recovery was of 100.02%.This method has advantages including high accuracy,rapidly,and convenience.

关 键 词：间叔丁基苯乙醚 高效液相色谱 分析 

分 类 号：O657.72[理学—分析化学]