甲状腺良性结节微波消融疗效超声相关因素分析  

Analysis of ultrasonic factors related to the efficacy of microwave ablation of benign thyroid nodules

作　　者：沙晓溪[1] 饶程义 陈园园 袁艺 张嬿[1] SHA Xiaoxi;RAO Chengyi;CHEN Yuanyuan;YUAN Yi;ZHANG Yan(Department of Ultrasound,Hospital of Chengdu University of Traditional Chinese Medicine,Sichuan Province,Chengdu,Sichuan,610072,China)

机构地区：[1]四川省成都中医药大学附属医院超声医学科,四川成都610072

出　　处：《当代医学》2021年第32期1-3,共3页Contemporary Medicine

基　　金：四川省成都中医药大学附属医院院基金(2016-D-YY-13)。

摘　　要：目的分析不同超声评估指标与甲状腺结节微波消融疗效的相关性,旨在促进提高疗效。方法选取2017年3月至2018年10月于本院进行甲状腺良性结节微波消融术的患者108例,术前运用常规超声结合超声造影(CEUS)评估甲状腺结节各项超声指标,包括结节最大径、体积、内部回声、血供,分析上述指标与疗效间的相关性。结果治疗前与治疗后6个月及1年的结节体积比较差异均有统计学意义(P<0.05),微波消融后1年总有效率92%。结节术前最大径、体积、血供与疗效均呈负相关(r<0,P<0.05)。治疗1年后,最大直径<1 cm、结节及体积<3 mL的疗效显著[VRR分别为(93±14)%、(86±19)%],直径≥3 cm疗效不佳,VRR为(34±30)%,囊性及囊性为主结节平均体积缩小率(VRR)较大,VRR分别为(100±42)%、(84±22)%。结论甲状腺结节大小、血供、性状均是影响疗效的重要因素,对上述指标进行准确评估,有助于提高临床疗效及预估远期疗效,更利于医患间的沟通。Objective To analyze the correlation between different ultrasound evaluation indexes and the efficacy of microwave ablation of thyroid nodules in order to improve the efficacy.Methods 108 patients who underwent microwave ablation of benign thyroid nodules in our hospital from March 2017 to October 2018 were selected.Before the operation,conventional ultrasound combined with CEUS were used to evaluate the maximum diameter,volume,internal echo and blood supply of the nodules.Finally,the correlation between the above indexes and the curative effect were analyzed.Results There was statistically significant differences in the volume of nodules before treatment and 6 months and 1 year after treatment(P<0.05),and the overall effective rate at 1 year after microwave ablation was 92%.The preoperative maximum diameter,volume,blood supply were negatively correlated with the therapeutic effect(r<0,P<0.05).After 1 year of treatment,nodules with the maximum diameter<1 cm and the volume<3 mL had significant curative effect[with VRR of(93±14)%and(86±19)%],respectively,while the nodules with a diameter≥3 cm had poor therapeutic effect,the VRR was(34±30)%.The mean volume reduction rate(VRR)of cystic and cystic main nodules were larger,with VRR of(100±42)%and(84±22)%,respectively.Conclusion The nodule size,blood supply,characteristicsare were all important factors affecting the efficacy.Accurate evaluation of the above indicators is helpful to improve the clinical curative effect and predict the long-term curative effect,and it is also more conducive to the communication between doctors and patients.

关 键 词：超声 超声造影 甲状腺结节 微波消融 

分 类 号：R581[医药卫生—内分泌]