不同的血压控制目标值对低体重指数慢性心衰患者临床疗效的影响  

Influence of different blood pressure control target values on clinical efficacy of patients with low body mass index and chronic heart failure

作　　者：黎志勇 苏玉蓉 蔡剑玲 孙金剑 张素华 曾南萍 LI Zhiyong;SU Yurong;CAI Jianling;SUN Jinjian;ZHANG Suhua;ZENG Nanping(Comprehensive Internal Medicine,General Hospital of Pingxiang Mining Group Co.,Ltd,Pingxiang,Jiangxi,337000,China)

机构地区：[1]萍乡矿业集团有限责任公司总医院综合内科,江西萍乡337000

出　　处：《当代医学》2021年第32期45-47,共3页Contemporary Medicine

基　　金：江西省卫生计生委科技计划项目(20204467)。

摘　　要：目的探讨不同血压控制目标值对低体重指数慢性心衰患者的临床疗效。方法选取2019年5月至2020年12月本院收治的80例低体重指数慢性心衰患者,随机分为实验1组和实验2组,每组40例。实验1组血压控制目标值为140~120/75~90 mmHg;实验2组血压控制目标值为119~100/60~74 mmHg。两组均给予常规抗心衰治疗,比较两组临床疗效、心脏左室舒张末期及收缩末期内径、心脏彩超EF值、NT-proBNP、6 min步行实验、不良反应发生情况及再入院情况。结果实验2组治疗总有效率明显高于对照组,差异有统计学意义(P<0.05);治疗后,两组左室舒张末期内径、左室收缩末期内径均短于治疗前,且实验2组短于实验1组,差异有统计学意义(P<0.05);实验2组心脏彩超EF值、6 min步行实验均明显高于实验1组;实验2组血浆NT-proBNP明显低于实验1组,差异有统计学意义(P<0.05);两组再次入院率比较差异无统计学意义。结论将血压目标值控制在BP 119~100/60~74 mmHg,可提升低体重指数慢性心力衰竭患者的治疗效果及生活质量,值得临床推广运用。Objective To investigate the clinical effect of different blood pressure control target values on patients with chronic heart failure with low body mass index.Methods 80 patients with chronic heart failure with low body mass index admitted to our hospital from May 2019 to December 2020 were selected and they were randomly divided into experimental group 1 and experimental group 2,with 40 cases in each group.The target value of blood pressure control in experimental group 1 was 140-120/75-90 mmHg.The target values of blood pressure control in experimental group 2 were 119-100/60-74 mmHg.Routine antiheart failure therapy was given in both groups.Clinical efficacy,end-diastolic and end-systolic heart diameter of left ventricle,EF value of heart color ultrasound,NT-proBNP,6 min walking test,adverse reactions and readmission were compared between two groups.Results The total effective rate of experimental group 2 was significantly higher than that of control group,the difference was statistically significant(P<0.05).After treatment,left ventricular end-diastolic diameter and left ventricular end-systolic diameter in both groups were shorter than before treatment,and experimental group 2 was shorter than experimental group 1,the difference was statistically significant(P<0.05).EF value and 6 min test in experimental group 2 were significantly higher than those in experimental group 1.Plasma NT-proBNP in experimental group 2 was significantly lower than that in experimental group 1,and the difference was statistically significant(P<0.05).There was no significant difference in readmission rate between the two groups.Conclusion Controlling the target value of blood pressure in the range of BP 119-100/60-74 mmHg can improve the treatment effect and quality of life of patients with chronic heart failure with low body mass index,which is worthy of clinical application.

关 键 词：血压控制目标值 低体重指数 慢性心力衰竭 随机对照实验 

分 类 号：R541.6[医药卫生—心血管疾病]