2016~2019年我院住院患者HCV抗体检测结果分析  

Analysis of HCV antibody detection results of inpatients in a hospital from 2016 to 2019

作　　者：刘金峰 陈展泽 林静 梁敏锋 LIU Jin-feng;CHEN Zhan-ze;LIN Jing;LIANG Min-feng(Department of Infectious Diseases,Foshan First People's Hospital,Foshan Hospital affiliated to Sun Yat-sen University,Foshan 528000,China)

机构地区：[1]佛山市第一人民医院(中山大学附属佛山医院)感染科,广东佛山528000

出　　处：《黑龙江医药科学》2021年第5期143-145,共3页Heilongjiang Medicine and Pharmacy

摘　　要：目的:回顾性分析2016~2019年我院住院患者丙型肝炎病毒(HCV)的抗体检测结果。方法:收集2016-01-01~2019-12-30我院各科室428617例住院患者,均应用酶联免疫吸附试验(ELISA)对HCV抗体进行检测,分析比较不同年龄阶段、不同性别HCV抗体阳性率的差异,以及除感染科以外的其他科室HCV抗体的分布情况。结果:共收集血清标本428617份,其中HCV抗体阳性1084份,总阳性率为0.25%,其中男性阳性765例,女性阳性319例;除感染病区外HCV抗体阳性共909份,总阳性率为0.21%,其中男617例,女292例。男性HCV抗体阳性率70.57%显著高于女性19.56%,差异有统计学意义(P<0.05);不同年龄段之间HCV抗体阳性率不同,其中0~19岁HCV阳性率为0.65%最低,40~49岁HCV阳性率为37.64%最高,其次为50~59岁HCV阳性率为18.54%,差异有统计学意义(P<0.05)。结论:我院HCV抗体阳性率处于全国较低水平,但总体上感染水平趋于稳定,大致反映出该地区人群HCV感染状况,在感染趋势上存在明显的性别、年龄差异,男性多于女性,40~60岁为HCV感染高发年龄段,医院应当加强筛查。Objective:To retrospectively analyze the hepatitis C virus(HCV)antibody detection results of inpatients in Foshan Hospital affiliated to Sun Yat-sen University from 2016 to 2019.Methods:A total of 428,617 inpatients in various departments of our hospital were collected from January 1,2016 to December 30,2019.The HCV antibody was detected by ELISA.The difference of HCV antibody positive rate in different age groups and genders was analyzed and compared.Analyze the distribution of HCV antibody in other departments except infection department.Results:The serum samples of 428,617 patients were detected,of which 1084 were positive for HCV antibody,765 were male and 319 were female,the total positive rate was 0.25%.There were 909 cases of HCV antibody positive in other departments except infection department,including 617 males and 292 females,with a total positive rate of 0.21%.The positive rate of HCV antibody in male 70.57 was significantly higher than that in female 19.56%,the difference was statistically significant(P<0.05).HCV antibody positive rate is different among different age groups.The lowest HCV positive rate was 0.65%in 0~19 years.The positive rate of HCV in 40 to 49 years was 37.64%.The positive rate of HCV in 50~59 years was 18.54%,ranking second.The differences were statistically significant(P<0.05).Conclusion:The positive rate of HCV antibody in our hospital is at a low level in China,and the overall infection level tends to be stable and controllable.There are obvious differences in gender and age in the trend of infection,with more males than females.The age group with high incidence of HCV infection is 40~60 years old.The results can roughly reflect the HCV infection status in this area.

关 键 词：丙型肝炎病毒 抗体检测 住院患者 年龄 性别 

分 类 号：R512.63[医药卫生—内科学]