温针灸治疗膝关节痛风性关节炎湿热蕴结证患者的疗效及对关节疼痛、关节功能和血清炎症指标的影响  

Effect of warm acupuncture for serum inflammatory factors,joint pain and joint function in patients with knee gouty arthritis of damp-heat accumulation

作　　者：张慧森 刘健[1] 温石磊 田斌武 ZHANG Huisen;LIU Jian;WEN Shilei;TIAN Binwu(Department of Orthopedics,Baoding No.1 Hospital of TCM,Baoding,Hebei 071000)

机构地区：[1]河北省保定市第一中医院骨科,河北保定071000

出　　处：《河北中医》2021年第7期1170-1173,共4页Hebei Journal of Traditional Chinese Medicine

基　　金：2018年保定市科学技术研究与发展指导计划项目(编号:18ZF102)。

摘　　要：目的观察温针灸治疗膝关节痛风性关节炎湿热蕴结证的疗效及对患者关节疼痛、关节功能和血清炎症指标的影响。方法将105例膝关节痛风性关节炎湿热蕴结证患者按照随机数字表法分为2组。对照组53例(脱落2例)予西医常规治疗,治疗组52例(脱落1例)在对照组治疗基础上联合温针灸治疗。2组均治疗2周。比较2组治疗前后疼痛视觉模拟评分(VAS)、膝关节运动功能Lysholm评分及血清炎症指标白细胞介素1β(IL-1β)、白细胞介素18(IL-18)、C反应蛋白(CRP)水平,并统计疗效。结果治疗组总有效率90.20%(46/51),对照组总有效率74.51%(38/51),治疗组疗效优于对照组(P<0.05)。治疗后2组疼痛VAS均较本组治疗前降低(P<0.05),且治疗后治疗组低于对照组(P<0.05)。治疗后2组Lysholm各项评分及总分均较本组治疗前升高(P<0.05),且治疗后治疗组均高于对照组(P<0.05)。治疗后2组血清IL-1β、IL-18、CRP水平均较本组治疗前降低(P<0.05),且治疗后治疗组均低于对照组(P<0.05)。结论温针灸可提高膝关节痛风性关节炎湿热蕴结证的疗效,减轻患者关节疼痛,降低炎症指标的水平,改善关节功能。Objective To observe the effect of warm acupuncture for serum inflammatory factors,joint pain and joint function in patients with knee gouty arthritis(GA)of damp-heat accumulation.Methods Totally 105 patients with knee GA(damp-heat accumulation)were randomly divided into 2 groups.53 cases(2 cases of shedding)in control group were treated with routine western medicine treatment,and 52 cases(1 case of shedding)in treatment group with warm acupuncture on the basis of control group.Treated for 2 weeks,aiming to compare level of inflammatory factors such as serum interleukin 1β(IL-1β),IL-18,C reactive protein(CRP),visual analogue score(VAS)for pain,Lysholm knee score(LKS);the curative effect was counted.Results The total effective rates in treatment group and control group were 90.20%(46/51)and 74.51%(38/51),respectively,the curative effect being better in treatment group than control group(P<0.05).After treatment,serum IL-1β,IL-18,CRP in groups were decreased(P<0.05),which decreased notably in treatment group when compared with control group(P<0.05);VAS scores in groups remarkably decreased(P<0.05),improvement of which in treatment group were significantly better(P<0.05);LKS scores in groups were increased,which were significantly higher in treatment group than in control group(P<0.05).Conclusion For patients with knee GA(damp-heat accumulation),warm acupuncture can improve the curative effect,relieve joint pain,reduce the level of inflammatory factors and improve joint function.

关 键 词：关节炎 痛风性 膝关节 温针疗法 

分 类 号：R684.3[医药卫生—骨科学] R245.315[医药卫生—外科学]