住院患者急性呼吸道病毒感染流行病学特征及干预措施  

Epidemiological study and intervention measures of acute respiratory virus infection in hospitalized patients

作　　者：胡频频 廖瑶 王陈玲 HU Pin-pin;LIAO Yao;WANG Chen-ling(Department of Laboratory Medicine,Affiliated Traditional Chinese Medicine Hospital of Chengdu Medical College,Chengdu 610300)

机构地区：[1]成都医学院附属中医医院医学检验科,成都610300

出　　处：《公共卫生与预防医学》2021年第6期63-66,共4页Journal of Public Health and Preventive Medicine

摘　　要：目的了解住院患者急性呼吸道病毒感染的流行病学特征,为临床诊疗提供参考,制定相关干预措施。方法选取成都医学院附属中医医院2019年3月至2021年3月收治呼吸道病毒感染住院患者414例,采用免疫荧光法定性检测副流感病毒1-3型、甲型流感病毒、呼吸道合胞病毒(RSV)、乙型流感病毒、腺病毒。结果414例ARTI患者中呼吸道病毒阳性例数为84例,阳性检出率为20.29%(84/414),单一病毒感染阳性患者为76例,阳性检出率为18.36%(76/414);混合感染性患者为8例,阳性检出率为1.93%(8/414),病毒感染最常见的病原体为甲型流感病毒(25.00%)、乙型流感病毒(20.23%)和RSV(17.86%)。不同年龄段ARTI患者病毒阳性检出率差异有统计学意义(χ^(2)=84.692,P<0.05);1~8岁月组呼吸道病毒检出率最高(38.93%)。7种病毒阳性检出率差异有统计学意义(P<0.05);病毒混合感染患者在主要为8岁以下患儿;不同季节ARTI患者病毒阳性检出率差异有统计学意义(χ^(2)=27.291,P<0.05);PIV1、PIV2、ADV和混合感染检出率的季节分布差异无统计学意义(P>0.05);PIV3阳性检出率最高为春季(4.04%),RSV在春季和冬季的阳性检出率分别为(24.24%)和(25.20%);甲型流感病毒和乙型流感病毒阳性检出率最高在冬季(9.45%)和(7.09%);不同临床诊断ARTI患者病毒阳性检出率差异有统计学意义(χ^(2)=17.452,P<0.05);PIV2、PIV3、甲型流感病毒和乙型流感病毒阳性检出率差异有统计学意义(P<0.05);支气管肺炎病毒阳性检出率最高(27.48%)。结论急性呼吸道病毒感染患者以RSV感染最为常见,多发生在秋冬季,其中主要临床表现为支气管肺炎,主要感染人群为8岁以下患儿,今后应加强对呼吸道合胞病毒的监测。Objective To understand the epidemiological characteristics of acute respiratory virus infection in hospitalized patients,and to provide reference for clinical diagnosis and treatment,and to develop relevant intervention measures.Methods A total of 414 hospitalized patients with respiratory virus infection admitted to our hospital from March 2019 to March 2021 were selected.Immunofluorescence method was used to qualitative detect parainfluenza virus type 1-3,influenza A virus,respiratory syncytial virus(RSV),influenza B virus and adenovirus.Results Among the 414 ARTI patients,84 cases were positive for respiratory virus,with a positive detection rate of 20.29%(84/414).76 cases were positive for single virus infection,with a positive detection rate of 18.36%(76/414).The positive detection rate was 1.93%(8/414).The most common pathogens of virus infection were influenza A virus(25.00%),influenza B virus(20.23%)and RSV(17.86%).There was statistical significance in the positive rate of ARTI among different age groups(χ^(2)=84.692,P<0.05).The positive rate of respiratory virus in 1-8 years group was the highest(38.93%).There was statistical significance in the positive rate of 7 viruses(P<0.05).The patients with viral mixed infection were mainly children under 8 years old;There was statistical significance in the positive rate of ARTI in different seasons(χ^(2)=27.291,P<0.05).There was no significant difference in the seasonal distribution of PIV1,PIV2,ADV and mixed infection rates(P>0.05).The positive rate of PIV3 was the highest in spring(4.04%),and the positive rate of RSV in spring and winter was 24.24%and 25.20%,respectively.The positive rates of influenza A virus and influenza B virus were the highest in winter(9.45%)and(7.09%).There was statistical significance in the positive rate of ARTI among different clinical diagnoses(χ^(2)=17.452,P<0.05).The positive rates of PIV2,PIV3,influenza A virus and influenza B virus were significantly different(P<0.05).The positive rate of bronchopneumonia virus was the highe

关 键 词：住院患者 急性呼吸道病毒感染 干预措施 

分 类 号：R181[医药卫生—流行病学]