鲜竹沥中1个新的萘酚  

A New Naphthol from Xianzhuli

作　　者：喻何云 赵敏敏 任琦 姚金龙 罗跃华 付辉政 YU Heyun;ZHAO Minmin;REN Qi;YAO Jinlong;LUO Yuehua;FU Huizheng(Jiangxi Institute for Drug Control,NMPA Key Laboratory of Quality Evaluation of Traditional Chinese Patent Medicine,Jiangxi Province Engineering Research Center of Drug and Medical Device Quality,Nanchang Jiangxi 330029,China;Jiangxi Pharmaceuticai School,Nanchang Jiangxi 330001,China)

机构地区：[1]江西省药品检验检测研究院,国家药品监督管理局中成药质量评价重点实验室,江西省药品与医疗器械质量工程技术研究中心,江西南昌330029 [2]江西省医药学校,江西南昌330001

出　　处：《药品评价》2021年第18期1089-1091,共3页Drug Evaluation

基　　金：江西省重点研发计划项目(20171BBG70103);国家药典委员会药品标准提高项目(2019Z085)。

摘　　要：目的:研究特色中药鲜竹沥的化学成分。方法:采用正相和反相硅胶柱色谱以及制备型反相液相色谱进行分离和纯化,再运用NMR、MS等波谱手段鉴定化合物结构。结果:从鲜竹沥药材中分离获得了1个化合物,鉴定为5-(4-羟基-3,5-二甲氧基苯基)-1,3-二甲氧基-2-萘酚。结论:化合物1为新化合物,命名为鲜竹沥素A。Objective:To study the chemical constituents from Xianzhuli.Methods:The compounds were prepared by normalphase andreversed-phase silica gel column chromatography and preparative liquid chromatography,and their structures were identified by NMR,MS and other spectra data.Results:One compound was isolated from medicinal materials Xianzhuli and elucidated as 5-(4-hydroxy-3,5-dimethoxyphenyl)-2,4-dimethoxy-3-naphthol.Conclusion:Compound 1 was a new compound named Xianzhuli A.

关 键 词：禾本科 鲜竹沥 化学成分 5-(4-羟基-3 5-二甲氧基苯基)-1 3-二甲氧基-2-萘酚 鲜竹沥素A 

分 类 号：R284.1[医药卫生—中药学]