评价纳络酮对重度酒精中毒患者在院前急救中的疗效及安全性  

Objective to evaluate the efficacy and safety of naloxone in pre hospital emergency treatment of patients with severe alcoholism

作　　者：杨雨贝 Yang Yubei(Emergency department ofPengzhou people's Hospital,Chengdu 611930,Sichuan)

机构地区：[1]彭州市人民医院急诊科,四川成都611930

出　　处：《人人健康》2021年第20期80-82,共3页Health for Everyone

摘　　要：目的:对纳洛酮在重度酒精中毒院前急救中的应用价值进行分析。方法:选择2019年5月至2020年5月收治30例重度酒精中毒的院前急救患者作为该次研究对象,均进行常规院前急救,另随机选取16例患者加用纳洛酮,并视为实验组,另14例患者不再做任何处理.视为对照组,比较两组患者治疗效果。结果:实验组治疗总有效率高于对照组、实验组动脉血气指标改善优于对照组、实验组总不良反应发生率低于对照组、实验组血清β-内啡肽水平低于对照组,统计学意义明显P<0.05。结论:在重度酒精中毒院前急救中使用纳洛酮不仅有着较高的安全性,更能提高救治成功率,具有推广应用价值。Objective:to analyze the application value of naloxone in pre hospital emergency treatment of severe alcoholism.Methods:from May 2019 to may 2020,30 p«itients with severe alcoholism were selected as the research object,and all of them were given routine pre hospital emergency care.Another 16 patients were randomly selected and treated with naloxone as the experimental group.The other 14 patients were treated as the control group without any treatment.Results:the total effective r«ite of the experimental group was higher than that of the control group,the improvement of arterial blood gas index of the experimental group was better than that of the control group,the total adverse reaction rate of the experimental group was lower than that of the control group,and the serum p_endorphin level of the experimental group w«is lower than that of the control group,with statistical significance(P<0.05).Conclusion:the use of naloxone in pre hospit«il emergency treatment of severe alcoholism not only has higher safety,but also can improve the success rate of treatment,which has the value of popularization and application.

关 键 词：纳洛酮 重度 酒精 中毒 院前急救 

分 类 号：R47[医药卫生—护理学]