体外受精-胚胎移植前宫腔内环境评估及处理的临床应用进展  

Advances in clinical application of intrauterine environment assessment and treatment before in vitro fertilization-embryo transfer

作　　者：王媛媛 龚照 刘文娟 阮建兴[1] 翁慧男[1] 刘风华[1] Wang Yuanyuan;Gong Zhao;Liu Wenjuan;Ruan Jianxing;Weng Huinan;Liu Fenghua(Reproductive Medicine Center,Guangdong Women and Children Hospital,Guangzhou 511400,China)

机构地区：[1]广东省妇幼保健院生殖健康与不孕症科,广州511400

出　　处：《国际医药卫生导报》2021年第21期3285-3288,共4页International Medicine and Health Guidance News

基　　金：国家重点研发计划课题(2018YFC1002604);广东省卫济医学发展基金会临床研究项目(K-202104-2)。

摘　　要：宫腔内环境是体外受精-胚胎移植(in vitro fertilization and embryo transfer,IVF-ET)成功的必要条件之一。在不孕女性中,宫腔内异常病变发生率为10%~15%,而在反复种植失败(repeated implantation failure,RIF)的患者中,这一比例高达50%。宫腔内异常病变可能由一个或多个病因引起,某些异常情况还可能重复出现。各类宫腔内异常病变均可能影响妊娠结局。恰当的评估及处理有助于提高IVF-ET的临床妊娠率。尤其在RIF患者当中,应进行多角度的评估,必要时重复评估并进行处理。本文拟对IVF-ET前宫腔内环境的评估及处理的临床应用进展进行综述。Intrauterine environment is one of the necessary conditions for the success of in vitro fertilization and embryo transfer(IVF-ET).In infertile women,the incidence of intrauterine abnormalities is 10%-15%;and in patients with repeated implantation failure(RIF),this proportion is as high as 50%.Intrauterine abnormalities may be caused by one or more causes,and some abnormal conditions may recur.Various types of intrauterine abnormalities may affect the outcomes of pregnancy.Appropriate evaluation and treatment can help improve the clinical pregnancy rate of IVF-ET.For RIF patients,a multi-angle evaluation should be carried out,and the evaluation and treatment should be repeated if necessary.This article intends to review the progress of clinical application in the evaluation and treatment of intrauterine environment before IVF-ET.

关 键 词：宫腔内环境 宫腔镜检查 体外受精-胚胎移植 反复种植失败 

分 类 号：R714.8[医药卫生—妇产科学]