男男性行为者对HIV非职业暴露后预防的认知及相关因素分析  

Cognition and related factors on the use of HIV non-occupational post-exposure prevention among men who have sex with men

作　　者：杨雪 李杰 王博 韩晶[4] 王辉[5] 宋兵 刘俊 王丽艳 庞琳[1] 张广[1] 汤后林[1] 刘童童[9] Yang Xue;Li Jie;Wang Bo;Han Jing;Wang Hui;Song Bing;Liu Jun;Wang Liyan;Pang Lin;Zhang Guang;Tang Houlin;Liu Tongtong(National Center for AIDS/STD Control and Prevention,Chinese Center for Disease Control and Prevention,Beijing 102206,China;Chinese Association of STD and AIDS Prevention and Control,Beijing 100050,China;Beijing Youan Hospital,Capital Medical University,Beijing 100069,China;Beijing Ditan Hospital,Capital Medical University,Beijing 100015,China;The Third People's Hospital of Shenzhen,Shenzhen 518112,China;The Fifth Medical Center of General Hospital of Chinese People's Liberation Army,Beijing 100039,China;The Third People's Hospital of Kunming,Kunming 650041,China;People's Medical Investment Management Limited Company,People's Medical Publishing House,Beijing 100021,China;Chinese Health Education Center,Beijing 100011,China)

机构地区：[1]中国疾病预防控制中心性病艾滋病预防控制中心,北京102206 [2]中国性病艾滋病防治协会,北京100050 [3]首都医科大学附属北京佑安医院,北京100069 [4]首都医科大学附属北京地坛医院,北京100015 [5]深圳市第三人民医院,518112 [6]中国人民解放军总医院第五医学中心,北京100039 [7]昆明市第三人民医院,650041 [8]人民卫生出版社人卫投资管理(北京)有限公司,北京100021 [9]中国健康教育中心,北京100011

出　　处：《中华流行病学杂志》2021年第10期1840-1845,共6页Chinese Journal of Epidemiology

摘　　要：目的了解MSM对HIV非职业暴露后预防(nPEP)的认知情况,以及使用nPEP的相关因素。方法 2019年3月15日至4月14日,采用滚雪球抽样方法,分别在北京市、深圳市和昆明市MSM社会组织招募年龄≥18岁男性、最近3个月发生过男男性行为、听说过HIV nPEP等符合条件的研究对象,通过"i卫士"收集人口学、行为学特征、nPEP基本知识及其咨询和使用情况。采用logistic回归模型对是否使用nPEP的相关因素进行分析。结果共调查1 809人,nPEP基本知识知晓率为39.8%(720/1 809),33.4%(605/1 809)咨询过nPEP,15.0%(271/1 809)使用过nPEP。多因素logistic回归分析结果显示,研究对象使用nPEP的相关因素包括最近3个月与男性HIV感染者发生过性行为(OR=2.58,95%CI:1.64-4.07)、最近1年HIV检测次数≥2次(OR=2.47,95%CI:1.28-5.11)、nPEP基本知识知晓(OR=0.70,95%CI:0.49-0.99)、咨询过nPEP(OR=70.98,95%CI:40.51-136.83)。结论 MSM对nPEP认知不足,应加强MSM的nPEP相关宣传教育,促进MSM发生HIV暴露后尽快使用nPEP。Objective To understand the cognition and related factors on the use of HIV non-occupational post-exposure prophylaxis(nPEP)among men who have sex with men(MSM).Methods The snowballing method was applied to recruit research subjects who were≥18 years old,had sex with men in the past three months,and were aware of nPEP in MSM groups in Beijing,Shenzhen,and Kunming from March 15 to April 14,2019.Data on social demographics,behavioral characteristics,basic knowledge of nPEP,consultation,and using nPEP were collected through"i guardian Platform".The logistic regression model was used to analyze the related factors affecting the use of nPEP.Results Among 1809 investigated,39.8%(720 persons)were aware of the basic knowledge of nPEP,33.4%(605 persons)had consulted nPEP,and 15.0%(271 persons)had used nPEP.In addition,multivariate logistic regression analysis showed that factors as whether to have sex with men infected with HIV in the last three months(OR=2.58,95%CI:1.64-4.07),the frequency of HIV testing in the past year(OR=2.47,95%CI:1.28-5.11),nPEP knowledge awareness(OR=0.70,95%CI:0.49-0.99),whether to consult nPEP(OR=70.98,95%CI:40.51-136.83)were related to the use of nPEP.Conclusions MSM still have poor cognition of nPEP.It is necessary to strengthen the publicity and education of nPEP in MSM and promote the use of nPEP after HIV exposure as soon as possible.

关 键 词：艾滋病病毒 男男性行为者 非职业暴露后预防 相关因素 

分 类 号：R512.91[医药卫生—内科学]