Regulation of bone metabolism mediated byβ-adrenergic receptor and its clinical application  

作　　者：Xue-Ping Zhong Wen-Fang Xia 

机构地区：[1]Department of Endocrinology,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430022,Hubei Province,China

出　　处：《World Journal of Clinical Cases》2021年第30期8967-8973,共7页世界临床病例杂志

基　　金：Supported by National Natural Sciences Foundation of China,No.81200649;Natural Sciences Foundation of Hubei Province of China,No.2016CFB425;Fundamental Research Funds for the Central University,No.2016YXMS236.

摘　　要：Recent studies have confirmed thatβ-adrenergic receptors(β-ARs)are expressed on the surface of osteoblasts and osteoclasts,and that the sympathetic nervous system can regulate bone metabolism by activating them.β-AR blockers(BBs)are commonly used in the treatment of cardiovascular diseases in the elderly.It is important to investigate whether BBs have a beneficial effect on bone metabolism in the treatment of cardiovascular diseases,so as to expand their clinical application.This article reviews the effects of BB on bone metabolism and the progress of clinical research.

关 键 词：β-Adrenergic receptors Bone metabolism β-Adrenergic receptor blocker β-Adrenergic Skeletal system 

分 类 号：R969[医药卫生—药理学]